This IMSD proposal from Meharry Medical Center and Vanderbilt University is designed to help increase the number of disadvantaged minorities entering careers in science. The concept and mechanism for attaining this goal are constructed within the framework of the Vanderbilt/Meharry Alliance, a unique commitment on behalf of a front rank research university and a historically Black medical school to interact extensively on clinical care, biomedical research and research training. The goal is to preserve the unique beneficial characteristics of these two schools while leading to enhanced research and education at both institutions acting together. This IMSD proposal envisages bringing together two groups of minority students into an extensively mentored environment at the two schools. The first group would be members of a post baccalaureate program consisting of students with a future interest in a research career but would like more exposure to hands on science. In addition to research experience, this program provides extensive mentoring about the commitment and strategies necessary for such students to succeed in this endeavor. This program would be from 6 to 18 months in length. The second group would be students who have just matriculated into the Vanderbilt/Meharry Interdisciplinary Graduate programs, including a significant number fro Vanderbilt and from Meharry Brides to the Doctorate programs. The approach envisaged is that which would facilitate a subsequent development into outstanding research scientists by providing support at a time when many minority students feel stressed and challenged by what is often a highly unfamiliar new environment in terms of the educational institution, the learning strategies and the heavy dependence on laboratory instruction and the scientific literature. Much of the requested funding is directed towards student support and to associated faculty release time. However, we anticipate that new structures and interactions will be formed between the two alliance institutions during the time of this program. Much will depend upon a supportive and responsive interaction between the educational components of each institution and a part of this request is also to support this aspect of the Alliance.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM062459-02
Application #
6620455
Study Section
Special Emphasis Panel (ZGM1-MBRS-9 (SD))
Program Officer
Eckstrand, Irene A
Project Start
2002-04-01
Project End
2006-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
2
Fiscal Year
2003
Total Cost
$667,074
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Physiology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Doxie, Deon B; Greenplate, Allison R; Gandelman, Jocelyn S et al. (2018) BRAF and MEK inhibitor therapy eliminates Nestin-expressing melanoma cells in human tumors. Pigment Cell Melanoma Res 31:708-719
Shonesy, Brian C; Parrish, Walker P; Haddad, Hala K et al. (2018) Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biol Psychiatry 84:304-315
Steiner, Bradley D; Eberly, Allison R; Hurst, Melanie N et al. (2018) Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli. J Membr Biol 251:65-74
Lizama, Britney N; Palubinsky, Amy M; McLaughlin, BethAnn (2018) Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues. Neurochem Int 117:139-155
Infante Lara, Lorena; Fenner, Sabine; Ratcliffe, Steven et al. (2018) Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences. Nucleic Acids Res 46:2218-2233
Elion, David L; Jacobson, Max E; Hicks, Donna J et al. (2018) Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers. Cancer Res 78:6183-6195
Elion, David L; Cook, Rebecca S (2018) Genetic and Phenotypic Diversification of Heterogeneous Tumor Populations. Trends Mol Med 24:655-656
Durbin, Matthew D; Cadar, Adrian G; Chun, Young Wook et al. (2018) Investigating pediatric disorders with induced pluripotent stem cells. Pediatr Res 84:499-508
Kharade, Sujay V; Kurata, Haruto; Bender, Aaron M et al. (2018) Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992. Mol Pharmacol 94:926-937
Elmore, Zachary C; Guillen, Rodrigo X; Gould, Kathleen L (2018) The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole. Mol Biol Cell 29:1664-1674

Showing the most recent 10 out of 244 publications