A diverse educational and scientific community is a vital component for developing a robust work force that can address the technological and social challenges of the U.S. in a new global economy. However, the access of students from disadvantaged social and economic backgrounds to graduate education (Ph.D. level) is still low in comparison with individuals from more privileged socioeconomic groups. This disparity is amplified during academic life, resulting in a lack of faculty diversity at most U.S. universities.To address this problem, the Initiative for Maximizing Student Development (IMSD) program was established in 2008 at UCSD, which focuses on motivating, mentoring, and facilitating the transition of students from disadvantaged economic and social backgrounds and students with disabilities from college to graduate school. The UCSD-IMSD program is composed of three consecutive phases directed at mentoring students from their initial college education to the awarding of a Ph.D. in biomedical sciences. Phase 1 is directed at introducing freshmen students with no or limited prior research experience to scientific work via fundamental experimental instruction within the Basic Methodology Training Laboratory (BMTL). In this setting, students learn the essential research principles and skills (laboratory safety, basic techniques, data collection, and analysis) that will prepare them to participate in organized research projects. During Phase 2, students participate in hands-on, bench research projects under the mentorship of established, well-funded investigators. Thus, students are trained in several aspects of science, including experimental design, execution, data analysis and presentations, increasing their competitiveness as graduate school candidates. In addition, students are motivated to enroll into Ph.D. programs and assisted during the process. Students that are accepted in a UCSD graduate program (Phase 3) are mentored toward the completion of the Ph.D. work, are assisted in the application to fellowships and informed about various research careers, with special emphasis on postdoctoral training.

Public Health Relevance

The objective of this application is to motivate, mentor, and facilitate the transition of students from disadvantaged economic and social backgrounds, and students with disabilities into Ph.D. programs via a program that includes training, mentoring, and economical support.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
2R25GM083275-05
Application #
8214095
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Janes, Daniel E
Project Start
2008-03-01
Project End
2017-03-31
Budget Start
2012-04-04
Budget End
2013-03-31
Support Year
5
Fiscal Year
2012
Total Cost
$856,367
Indirect Cost
$58,598
Name
University of California San Diego
Department
Surgery
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Pandolfi, Erica C; Hoffmann, Hanne M; Schoeller, Erica L et al. (2018) Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration. Mol Neurobiol 55:8709-8727
Hoffmann, Hanne M; Trang, Crystal; Gong, Ping et al. (2016) Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. J Neurosci 36:3506-18
Lopez, Victor; Cauvi, David M; Arispe, Nelson et al. (2016) Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes. Cell Stress Chaperones 21:609-16
Lehmann, Jason S; Corey, Victoria C; Ricaldi, Jessica N et al. (2016) Whole Genome Shotgun Sequencing Shows Selection on Leptospira Regulatory Proteins During in vitro Culture Attenuation. Am J Trop Med Hyg 94:302-13
Williams, Michael R; Cauvi, David M; Rivera, Isabel et al. (2016) Changes in macrophage function modulated by the lipid environment. Innate Immun 22:141-51
Mirendil, H; Thomas, E A; De Loera, C et al. (2015) LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage. Transl Psychiatry 5:e541
Lehmann, Jason S; Matthias, Michael A; Vinetz, Joseph M et al. (2014) Leptospiral pathogenomics. Pathogens 3:280-308
NiƱo, Diego F; Cauvi, David M; De Maio, Antonio (2014) Itraconazole, a commonly used antifungal, inhibits Fc? receptor-mediated phagocytosis: alteration of Fc? receptor glycosylation and gene expression. Shock 42:52-9
Cauvi, David M; Williams, Michael R; Bermudez, Jose A et al. (2014) Elevated expression of IL-23/IL-17 pathway-related mediators correlates with exacerbation of pulmonary inflammation during polymicrobial sepsis. Shock 42:246-55
Armijo, Gabrielle; Okerblom, Jonathan; Cauvi, David M et al. (2014) Interaction of heat shock protein 70 with membranes depends on the lipid environment. Cell Stress Chaperones 19:877-86

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