The proposed research seeks to evaluate two recent hypotheses about the source of phonological errors in the speech of fluent aphasics: (1) Wernicke's aphasics exhibit disrupted processing within the phonological lexicon (Ellis, 1985), and (2) conduction aphasics exhibit disrupted phonemic string construction (Nespoulous et al., 1986). While each of these hypotheses appears to account for some aspects of phonological dysfunction in fluent aphasia, their generality is called into question by the variability of clinical symptoms associated with these syndromes. The proposed research will use longitudinal data to evaluate the above hypothesis. Wernicke's, conduction, and transcortical sensory aphasics will be examined with a battery of phonological encoding and decoding tests administered several times over the first 6 months post onset. To create more homogeneous experimental groups, each subject will be given a subdiagnosis on the basis of spontaneous speech (e.g., Wernicke's aphasia with semantic jargon). A clinically-based coding system for classifying production errors will be used both to determine this subdiagnosis and to identify the portion of the production data that will submitted to detailed phonological analysis. A model of word production will serve as the basis for generating the phonological analyses and for interpreting all data. It is anticipated that, by examining changes in phonological error patterns over time, the core behavior(s) needed to more precisely diagnose fluent aphasics will be identified, and, competing interpretations of error patterns will be disentangled. Better understanding of the evolution of fluent aphasic symptomatology will also provide invaluable information for the prognosis and rehabilitation of aphasic patients.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29NS025613-01A1
Application #
3564527
Study Section
Communication Sciences and Disorders (CMS)
Project Start
1988-09-01
Project End
1993-08-31
Budget Start
1988-09-01
Budget End
1989-08-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Kohn, S E; Smith, K L; Arsenault, J K (1990) The remediation of conduction aphasia via sentence repetition: a case study. Br J Disord Commun 25:45-60