I propose to continue along the path of my prior work in cancer epidemiology. That work will entail: 1) Analyses of routinely-collected data on cancer incidence. Local and national data will be used, both to generate clues as to the etiologies of cancer and to address practical issues of cancer prevention. 2) Cohort and population-based case-control studies of cancer. In addition to concluding a number of studies begun during the first cycle of funding from the Outstanding Investigator Grant, I plan to initiate others, likely including studies of: a) ovarian cancer in relation to galactose consumption and metabolism; and b) subsequent cancer incidence among women with infertility, with particular attention given to the type of infertility and its treatment. With colleagues in the laboratory, I will continue to explore ways of more precisely characterizing exposure or susceptibility that can be put to use in epidemiologic studies. 3) Refinement of epidemiologic methods relevant to the study of cancer. Emphasis will be given to development of analytic strategies to minimize bias in case-control studies which evaluate the efficacy of cancer screening modalities.
| Prescott, Jennifer; Setiawan, Veronica W; Wentzensen, Nicolas et al. (2015) Body Mass Index Genetic Risk Score and Endometrial Cancer Risk. PLoS One 10:e0143256 |
| Felix, Ashley S; Gaudet, Mia M; La Vecchia, Carlo et al. (2015) Intrauterine devices and endometrial cancer risk: a pooled analysis of the Epidemiology of Endometrial Cancer Consortium. Int J Cancer 136:E410-22 |
| Cote, Michele L; Alhajj, Tala; Ruterbusch, Julie J et al. (2015) Risk factors for endometrial cancer in black and white women: a pooled analysis from the Epidemiology of Endometrial Cancer Consortium (E2C2). Cancer Causes Control 26:287-296 |
| Chen, Maxine M; Crous-Bou, Marta; Setiawan, Veronica W et al. (2014) Exome-wide association study of endometrial cancer in a multiethnic population. PLoS One 9:e97045 |
| Setiawan, Veronica Wendy; Schumacher, Fredrick; Prescott, Jennifer et al. (2014) Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia. Carcinogenesis 35:2068-73 |
| Kamineni, Aruna; Weinmann, Sheila; Shy, Kirkwood K et al. (2013) Efficacy of screening in preventing cervical cancer among older women. Cancer Causes Control 24:1653-60 |
| Setiawan, Veronica Wendy; Yang, Hannah P; Pike, Malcolm C et al. (2013) Type I and II endometrial cancers: have they different risk factors? J Clin Oncol 31:2607-18 |
| Phipps, Amanda I; Doherty, Jennifer A; Voigt, Lynda F et al. (2011) Long-term use of continuous-combined estrogen-progestin hormone therapy and risk of endometrial cancer. Cancer Causes Control 22:1639-46 |
| Pocobelli, Gaia; Doherty, Jennifer A; Voigt, Lynda F et al. (2011) Pregnancy history and risk of endometrial cancer. Epidemiology 22:638-45 |
| Doherty, Jennifer A; Weiss, Noel S; Fish, Sherianne et al. (2011) Polymorphisms in nucleotide excision repair genes and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 20:1873-82 |
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