Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG001274-16
Application #
2048636
Study Section
Special Emphasis Panel (NSS)
Program Officer
Finkelstein, David B
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1994-04-01
Budget End
1997-01-31
Support Year
16
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of North Texas
Department
Biochemistry
Type
Schools of Osteopathy
DUNS #
110091808
City
Fort Worth
State
TX
Country
United States
Zip Code
76107
Dimitrijevich, S D; Paranjape, S; Wilson, J R et al. (1999) Effect of hyperbaric oxygen on human skin cells in culture and in human dermal and skin equivalents. Wound Repair Regen 7:53-64
Gracy, R W; Talent, J M; Zvaigzne, A I (1998) Molecular wear and tear leads to terminal marking and the unstable isoforms of aging. J Exp Zool 282:18-27
Talent, J M; Zvaigzne, A I; Agrawal, N et al. (1997) Effect of active-site modification on the terminal marking deamidation of triosephosphate isomerase. Arch Biochem Biophys 340:27-35
Montgomerie, J Z; Gracy, R W; Holshuh, H J et al. (1997) The 28K protein in urinary bladder, squamous metaplasia and urine is triosephosphate isomerase. Clin Biochem 30:613-8
Dickerson Jr, J E; Lou, M F; Gracy, R W (1995) Ascorbic acid mediated alteration of alpha-crystallin secondary structure. Curr Eye Res 14:163-6
Zhang, Y; Yuksel, K U; Gracy, R W (1995) Terminal marking of avian triosephosphate isomerases by deamidation and oxidation. Arch Biochem Biophys 317:112-20
Sun, A Q; Yuksel, K U; Gracy, R W (1995) Terminal marking of triosephosphate isomerase: consequences of deamidation. Arch Biochem Biophys 322:361-8
Yuksel, K U; Sun, A Q; Gracy, R W et al. (1994) The hinged lid of yeast triose-phosphate isomerase. Determination of the energy barrier between the two conformations. J Biol Chem 269:5005-8
Garza-Ramos, G; Tuena de Gomez-Puyou, M; Gomez-Puyou, A et al. (1994) Deamidation of triosephosphate isomerase in reverse micelles: effects of water on catalysis and molecular wear and tear. Biochemistry 33:6960-5
Sun, A Q; Yuksel, K U; Gracy, R W (1993) Limited proteolysis of triose-phosphate isomerase and characterization of the catalytically active peptide complex. J Biol Chem 268:26872-8

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