Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI014910-17
Application #
2060130
Study Section
Immunobiology Study Section (IMB)
Project Start
1978-04-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Pathology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Kulik, Liudmila; Chen, Kuan; Huber, Brigitte T et al. (2011) Human complement receptor type 2 (CR2/CD21) transgenic mice provide an in vivo model to study immunoregulatory effects of receptor antagonists. Mol Immunol 48:883-94
Sutkowski, Natalie; Chen, Gang; Calderon, German et al. (2004) Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen. J Virol 78:7852-60
Sutkowski, N; Conrad, B; Thorley-Lawson, D A et al. (2001) Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity 15:579-89
Hsu, P N; Wolf Bryant, P; Sutkowski, N et al. (2001) Association of mouse mammary tumor virus superantigen with MHC class II during biosynthesis. J Immunol 166:3309-14
Xu, L; Tay, C H; Huber, B T et al. (2000) Cloning of an infectious milk-borne mouse mammary tumor virus (MMTV) DNA from a mammary tumor that developed in an endogenous MMTV-free wild mouse. Virology 273:325-32
Yasui, D H; Genetta, T; Kadesch, T et al. (1998) Transcriptional repression of the IL-2 gene in Th cells by ZEB. J Immunol 160:4433-40
Gross, D M; Steere, A C; Huber, B T (1998) T helper 1 response is dominant and localized to the synovial fluid in patients with Lyme arthritis. J Immunol 160:1022-8
Arroyo, J; Winchester, E; McLellan, B S et al. (1997) Shared promoter elements between a viral superantigen and the major histocompatibility complex class II-associated invariant chain. J Virol 71:1237-45
Xie, H; Seward, R J; Huber, B T (1997) Cytokine rescue from glucocorticoid induced apoptosis in T cells is mediated through inhibition of IkappaBalpha. Mol Immunol 34:987-94
Beutner, U; McLellan, B; Kraus, E et al. (1996) Lack of MMTV superantigen presentation in MHC class II-deficient mice. Cell Immunol 168:141-7

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