Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37AI019411-11
Application #
3481028
Study Section
Special Emphasis Panel (NSS)
Project Start
1991-11-01
Project End
1992-07-31
Budget Start
1991-11-01
Budget End
1992-07-31
Support Year
11
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Seki, T; Selby, J; Haupl, T et al. (1998) Use of differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes. Arthritis Rheum 41:1356-64
Winchester, R; Chen, Y; Rose, S et al. (1995) Major histocompatibility complex class II DR alleles DRB1*1501 and those encoding HLA-DR13 are preferentially associated with a diminution in maternally transmitted human immunodeficiency virus 1 infection in different ethnic groups: determination by an a Proc Natl Acad Sci U S A 92:12374-8
Itescu, S; Rose, S; Dwyer, E et al. (1995) Grouping HLA-B locus serologic specificities according to shared structural motifs suggests that different peptide-anchoring pockets may have contrasting influences on the course of HIV-1 infection. Hum Immunol 42:81-9
Ritchlin, C; Dwyer, E; Bucala, R et al. (1994) Sustained and distinctive patterns of gene activation in synovial fibroblasts and whole synovial tissue obtained from inflammatory synovitis. Scand J Immunol 40:292-8
Itescu, S; Rose, S; Dwyer, E et al. (1994) Certain HLA-DR5 and -DR6 major histocompatibility complex class II alleles are associated with a CD8 lymphocytic host response to human immunodeficiency virus type 1 characterized by low lymphocyte viral strain heterogeneity and slow disease progression. Proc Natl Acad Sci U S A 91:11472-6
Dwyer, E; Itescu, S; Winchester, R (1993) Characterization of the primary structure of T cell receptor beta chains in cells infiltrating the salivary gland in the sicca syndrome of HIV-1 infection. Evidence of antigen-driven clonal selection suggested by restricted combinations of V beta J beta g J Clin Invest 92:495-502
Winchester, R; Dwyer, E; Rose, S (1992) The genetic basis of rheumatoid arthritis. The shared epitope hypothesis. Rheum Dis Clin North Am 18:761-83
Itescu, S; Mathur-Wagh, U; Skovron, M L et al. (1992) HLA-B35 is associated with accelerated progression to AIDS. J Acquir Immune Defic Syndr 5:37-45
Winchester, R; Dwyer, E (1991) MHC and autoimmune diseases: susceptibility to rheumatoid arthritis associated with a hydrophobic strip of alpha helix encoded by several MHC alleles. Immunol Ser 55:203-19
Steere, A C; Dwyer, E; Winchester, R (1990) Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med 323:219-23

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