Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI036040-21
Application #
7558262
Study Section
Special Emphasis Panel (NSS)
Program Officer
Berard, Diana S
Project Start
1988-12-01
Project End
2013-01-31
Budget Start
2009-02-01
Budget End
2010-01-31
Support Year
21
Fiscal Year
2009
Total Cost
$508,635
Indirect Cost
Name
Baylor College of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Ramani, Sasirekha; Stewart, Christopher J; Laucirica, Daniel R et al. (2018) Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection. Nat Commun 9:5010
Criglar, Jeanette M; Anish, Ramakrishnan; Hu, Liya et al. (2018) Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories. Proc Natl Acad Sci U S A 115:E12015-E12023
Hu, Liya; Sankaran, Banumathi; Laucirica, Daniel R et al. (2018) Glycan recognition in globally dominant human rotaviruses. Nat Commun 9:2631
Shanker, Sreejesh; Hu, Liya; Ramani, Sasirekha et al. (2017) Structural features of glycan recognition among viral pathogens. Curr Opin Struct Biol 44:211-218
Ramani, Sasirekha; Hu, Liya; Venkataram Prasad, B V et al. (2016) Diversity in Rotavirus-Host Glycan Interactions: A ""Sweet"" Spectrum. Cell Mol Gastroenterol Hepatol 2:263-273
Ogden, Kristen M; Prasad, B V Venkataram (2015) Quelling an innate response to dsRNA. Oncotarget 6:28535-6
Hu, Liya; Ramani, Sasirekha; Czako, Rita et al. (2015) Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus. Nat Commun 6:8346
Ogden, Kristen M; Hu, Liya; Jha, Babal K et al. (2015) Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist. J Virol 89:6633-45
Viskovska, Maria; Anish, Ramakrishnan; Hu, Liya et al. (2014) Probing the sites of interactions of rotaviral proteins involved in replication. J Virol 88:12866-81
Criglar, Jeanette M; Hu, Liya; Crawford, Sue E et al. (2014) A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly. J Virol 88:786-98

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