Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AR032461-11S1
Application #
3481562
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1982-07-01
Project End
1996-06-30
Budget Start
1992-08-06
Budget End
1993-06-30
Support Year
11
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Carnegie-Mellon University
Department
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Vanni, Steven; Lagerholm, B Christoffer; Otey, Carol et al. (2003) Internet-based image analysis quantifies contractile behavior of individual fibroblasts inside model tissue. Biophys J 84:2715-27
Lagerholm, B Christoffer; Vanni, Steven; Taylor, D Lansing et al. (2003) Cytomechanics applications of optical sectioning microscopy. Methods Enzymol 361:175-97
Abraham, V C; Krishnamurthi, V; Taylor, D L et al. (1999) The actin-based nanomachine at the leading edge of migrating cells. Biophys J 77:1721-32
Burton, K; Park, J H; Taylor, D L (1999) Keratocytes generate traction forces in two phases. Mol Biol Cell 10:3745-69
DeBiasio, R L; LaRocca, G M; Post, P L et al. (1996) Myosin II transport, organization, and phosphorylation: evidence for cortical flow/solation-contraction coupling during cytokinesis and cell locomotion. Mol Biol Cell 7:1259-82
Giuliano, K A; Post, P L; Hahn, K M et al. (1995) Fluorescent protein biosensors: measurement of molecular dynamics in living cells. Annu Rev Biophys Biomol Struct 24:405-34
Giuliano, K A; Taylor, D L (1995) Measurement and manipulation of cytoskeletal dynamics in living cells. Curr Opin Cell Biol 7:4-12
Post, P L; DeBiasio, R L; Taylor, D L (1995) A fluorescent protein biosensor of myosin II regulatory light chain phosphorylation reports a gradient of phosphorylated myosin II in migrating cells. Mol Biol Cell 6:1755-68
Giuliano, K A; Taylor, D L (1994) Fluorescent actin analogs with a high affinity for profilin in vitro exhibit an enhanced gradient of assembly in living cells. J Cell Biol 124:971-83
Post, P L; Trybus, K M; Taylor, D L (1994) A genetically engineered, protein-based optical biosensor of myosin II regulatory light chain phosphorylation. J Biol Chem 269:12880-7

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