Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA004186-42
Application #
2833993
Study Section
Special Emphasis Panel (NSS)
Program Officer
Gallahan, Daniel L
Project Start
1991-12-26
Project End
2004-12-31
Budget Start
2000-03-09
Budget End
2000-12-31
Support Year
42
Fiscal Year
2000
Total Cost
$441,780
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
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Placido, Diana; Brown 2nd, Bernard A; Lowenhaupt, Ky et al. (2007) A left-handed RNA double helix bound by the Z alpha domain of the RNA-editing enzyme ADAR1. Structure 15:395-404
Berger, I; Winston, W; Manoharan, R et al. (1998) Spectroscopic characterization of a DNA-binding domain, Z alpha, from the editing enzyme, dsRNA adenosine deaminase: evidence for left-handed Z-DNA in the Z alpha-DNA complex. Biochemistry 37:13313-21
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Herbert, A; Alfken, J; Kim, Y G et al. (1997) A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase. Proc Natl Acad Sci U S A 94:8421-6
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