Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA049870-15
Application #
6533127
Study Section
Special Emphasis Panel (NSS)
Program Officer
Wu, Roy S
Project Start
1989-05-01
Project End
2004-07-31
Budget Start
2002-08-26
Budget End
2003-07-31
Support Year
15
Fiscal Year
2002
Total Cost
$256,793
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Cui, Bing; Ghia, Emanuela M; Chen, Liguang et al. (2016) High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia. Blood 128:2931-2940
Mraz, Marek; Chen, Liguang; Rassenti, Laura Z et al. (2014) miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1. Blood 124:84-95
Cui, Bing; Chen, Liguang; Zhang, Suping et al. (2014) MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia. Blood 124:546-54
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Que, Xuchu; Widhopf 2nd, George F; Amir, Shahzada et al. (2013) IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitope. PLoS One 8:e65203
Chuang, Han-Yu; Rassenti, Laura; Salcedo, Michelle et al. (2012) Subnetwork-based analysis of chronic lymphocytic leukemia identifies pathways that associate with disease progression. Blood 120:2639-49
Steininger, Christoph; Widhopf 2nd, George F; Ghia, Emanuela M et al. (2012) Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen. Blood 119:2293-301
Choi, Michael Y; Kipps, Thomas J (2012) Inhibitors of B-cell receptor signaling for patients with B-cell malignancies. Cancer J 18:404-10
Ghia, Emanuela M; Widhopf 2nd, George F; Rassenti, Laura Z et al. (2011) Analyses of recombinant stereotypic IGHV3-21-encoded antibodies expressed in chronic lymphocytic leukemia. J Immunol 186:6338-44
Rieger, R; Whitacre, D; Cantwell, M J et al. (2009) Chimeric form of tumor necrosis factor-alpha has enhanced surface expression and antitumor activity. Cancer Gene Ther 16:53-64

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