Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DA003801-17
Application #
6534674
Study Section
Special Emphasis Panel (NSS)
Program Officer
Hillery, Paul
Project Start
1992-04-01
Project End
2007-12-31
Budget Start
2002-02-27
Budget End
2002-12-31
Support Year
17
Fiscal Year
2002
Total Cost
$435,425
Indirect Cost
Name
University of Connecticut
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
City
Storrs-Mansfield
State
CT
Country
United States
Zip Code
06269
Tyukhtenko, Sergiy; Rajarshi, Girija; Karageorgos, Ioannis et al. (2018) Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase. Sci Rep 8:1719
Mallipeddi, Srikrishnan; Zvonok, Nikolai; Makriyannis, Alexandros (2018) Expression, Purification and Characterization of the Human Cannabinoid 1 Receptor. Sci Rep 8:2935
Yu, Tianqi; Ganapathy, Suthakar; Shen, Ling et al. (2018) A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells. Oncotarget 9:6308-6319
Pava, Matthew J; Makriyannis, Alexandros; Lovinger, David M (2016) Endocannabinoid Signaling Regulates Sleep Stability. PLoS One 11:e0152473
Schindler, Charles W; Redhi, Godfrey H; Vemuri, Kiran et al. (2016) Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys. Neuropsychopharmacology 41:2283-93
Guo, Jason J; Yang, De-Ping; Tian, Xiaoyu et al. (2016) 17?-estradiol (E2) in membranes: Orientation and dynamic properties. Biochim Biophys Acta 1858:344-53
Tyukhtenko, Sergiy; Karageorgos, Ioannis; Rajarshi, Girija et al. (2016) Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES. J Biol Chem 291:2556-65
Panlilio, Leigh V; Thorndike, Eric B; Nikas, Spyros P et al. (2016) Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. Psychopharmacology (Berl) 233:1879-88
Janero, David R; Yaddanapudi, Suma; Zvonok, Nikolai et al. (2015) Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor. ACS Chem Neurosci 6:1400-10
Tyukhtenko, Sergiy; Chan, Karrie; Jiang, Rubin et al. (2015) Hydrogen-bonded His93 as a sensitive probe for identifying inhibitors of the endocannabinoid transport protein FABP7. Chem Biol Drug Des 85:534-40

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