Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37DK014038-23S1
Application #
3483047
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1977-12-01
Project End
1992-11-30
Budget Start
1991-12-01
Budget End
1992-11-30
Support Year
23
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Mahmood, Akhtar; Engle, Michael J; Alpers, David H (2002) Secreted intestinal surfactant-like particles interact with cell membranes and extracellular matrix proteins in rats. J Physiol 542:237-44
Mahmood, A; Engle, M J; Hultgren, S J et al. (2000) Role of intestinal surfactant-like particles as a potential reservoir of uropathogenic Escherichia coli. Biochim Biophys Acta 1523:49-55
Xie, Q; Alpers, D H (2000) The two isozymes of rat intestinal alkaline phosphatase are products of two distinct genes. Physiol Genomics 3:8-Jan
Goetz, G S; Mahmood, A; Hultgren, S J et al. (1999) Binding of pili from uropathogenic Escherichia coli to membranes secreted by human colonocytes and enterocytes. Infect Immun 67:6161-3
Eliakim, R; Goetz, G S; Rubio, S et al. (1997) Isolation and characterization of surfactant-like particles in rat and human colon. Am J Physiol 272:G425-34
Zhang, Y; Shao, J S; Xie, Q M et al. (1996) Immunolocalization of alkaline phosphatase and surfactant-like particle proteins in rat duodenum during fat absorption. Gastroenterology 110:478-88
Eliakim, R; Alpers, D H; Oren, R et al. (1996) Abundance of surfactant-like particles reflects mucosal integrity in patients with peptic ulcer disease. Gut 39:353-9
Dieckgraefe, B K; Santoro, S A; Alpers, D H (1996) Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis. Gastroenterology 110:58-71
Alpers, D H; Zhang, Y; Ahnen, D J (1995) Synthesis and parallel secretion of rat intestinal alkaline phosphatase and a surfactant-like particle protein. Am J Physiol 268:E1205-14
Yamagishi, F; Becich, M J; Evans, B A et al. (1994) Clearance of surfactant-like particle proteins from circulation in rats. Am J Physiol 266:G596-605

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