Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK028082-15
Application #
2138088
Study Section
Metabolism Study Section (MET)
Project Start
1981-03-01
Project End
1996-11-30
Budget Start
1996-02-20
Budget End
1996-11-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Douris, Nicholas; Desai, Bhavna N; Fisher, Ffolliott M et al. (2017) Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice. Mol Metab 6:854-862
Maratos-Flier, Eleftheria (2017) Fatty liver and FGF21 physiology. Exp Cell Res 360:2-5
Singhal, Garima; Fisher, Ffolliott Martin; Chee, Melissa J et al. (2016) Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas. PLoS One 11:e0148252
Singhal, Garima; Douris, Nicholas; Fish, Alan J et al. (2016) Fibroblast growth factor 21 has no direct role in regulating fertility in female mice. Mol Metab 5:690-8
Douris, Nicholas; Melman, Tamar; Pecherer, Jordan M et al. (2015) Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet. Biochim Biophys Acta 1852:2056-65
Hong, Shangyu; Moreno-Navarrete, Jose M; Wei, Xiaojing et al. (2015) Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nat Med 21:887-94
Fisher, Ffolliott M; Chui, Patricia C; Nasser, Imad A et al. (2014) Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets. Gastroenterology 147:1073-83.e6
Robins, S C; Stewart, I; McNay, D E et al. (2013) ?-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors. Nat Commun 4:2049
Koulmanda, Maria; Bhasin, Manoj; Awdeh, Zuheir et al. (2012) The role of TNF-? in mice with type 1- and 2- diabetes. PLoS One 7:e33254
Fisher, Ffolliott M; Kleiner, Sandra; Douris, Nicholas et al. (2012) FGF21 regulates PGC-1? and browning of white adipose tissues in adaptive thermogenesis. Genes Dev 26:271-81

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