Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK031450-16
Application #
2138636
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1982-01-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Stanford University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305

  Publications

Bhadra, Mayukh; Lee, Jung Yoon C; Cowley, Ryan E et al. (2018) Intramolecular Hydrogen Bonding Enhances Stability and Reactivity of Mononuclear Cupric Superoxide Complexes. J Am Chem Soc 140:9042-9045
Johnston, Esther M; Carreira, Cíntia; Dell'Acqua, Simone et al. (2017) Spectroscopic Definition of the CuZ° Intermediate in Turnover of Nitrous Oxide Reductase and Molecular Insight into the Catalytic Mechanism. J Am Chem Soc 139:4462-4476
Garcia-Bosch, Isaac; Cowley, Ryan E; Díaz, Daniel E et al. (2017) Substrate and Lewis Acid Coordination Promote O-O Bond Cleavage of an Unreactive L2CuII2(O22-) Species to Form L2CuIII2(O)2 Cores with Enhanced Oxidative Reactivity. J Am Chem Soc 139:3186-3195
Adam, Suzanne M; Garcia-Bosch, Isaac; Schaefer, Andrew W et al. (2017) Critical Aspects of Heme-Peroxo-Cu Complex Structure and Nature of Proton Source Dictate Metal-O(peroxo) Breakage versus Reductive O-O Cleavage Chemistry. J Am Chem Soc 139:472-481
Schaefer, Andrew W; Kieber-Emmons, Matthew T; Adam, Suzanne M et al. (2017) Phenol-Induced O-O Bond Cleavage in a Low-Spin Heme-Peroxo-Copper Complex: Implications for O2 Reduction in Heme-Copper Oxidases. J Am Chem Soc 139:7958-7973
Solomon, Edward I (2016) Dioxygen Binding, Activation, and Reduction to H2O by Cu Enzymes. Inorg Chem 55:6364-75
Arcos-López, Trinidad; Qayyum, Munzarin; Rivillas-Acevedo, Lina et al. (2016) Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106-115. Inorg Chem 55:2909-22
Solomon, Edward I; Hadt, Ryan G; Snyder, Benjamin E R (2016) Activating Metal Sites for Biological Electron Transfer. Isr J Chem 56:649-659
Tian, Shiliang; Liu, Jing; Cowley, Ryan E et al. (2016) Reversible S-nitrosylation in an engineered azurin. Nat Chem 8:670-7
Garcia-Bosch, Isaac; Cowley, Ryan E; Díaz, Daniel E et al. (2016) Dioxygen Activation by a Macrocyclic Copper Complex Leads to a Cu2O2 Core with Unexpected Structure and Reactivity. Chemistry 22:5133-7

Showing the most recent 10 out of 136 publications