Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK047618-17
Application #
6825769
Study Section
Special Emphasis Panel (NSS)
Program Officer
Haft, Carol R
Project Start
1989-01-01
Project End
2007-12-31
Budget Start
2005-01-01
Budget End
2005-12-31
Support Year
17
Fiscal Year
2005
Total Cost
$725,882
Indirect Cost
Name
Whitehead Institute for Biomedical Research
Department
Type
DUNS #
120989983
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Alvarez-Dominguez, Juan R; Bai, Zhiqiang; Xu, Dan et al. (2015) De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development. Cell Metab 21:764-776
Kim, Hye-Jin; Cho, Hyunjii; Alexander, Ryan et al. (2014) MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes. Diabetes 63:4045-56
Sun, Lei; Goff, Loyal A; Trapnell, Cole et al. (2013) Long noncoding RNAs regulate adipogenesis. Proc Natl Acad Sci U S A 110:3387-92
Trajkovski, Mirko; Lodish, Harvey (2013) MicroRNA networks regulate development of brown adipocytes. Trends Endocrinol Metab 24:442-50
Zhang, L; Sankaran, V G; Lodish, H F (2012) MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment. Leukemia 26:2310-6
Sun, Lei; Xie, Huangming; Mori, Marcelo A et al. (2011) Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol 13:958-65
Zhang, Lingbo; Flygare, Johan; Wong, Piu et al. (2011) miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1. Genes Dev 25:119-24
Xie, Huangming; Lim, Bing; Lodish, Harvey F (2009) MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 58:1050-7
Wong, G William; Krawczyk, Sarah A; Kitidis-Mitrokostas, Claire et al. (2009) Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J 23:241-58
Xie, Huangming; Sun, Lei; Lodish, Harvey F (2009) Targeting microRNAs in obesity. Expert Opin Ther Targets 13:1227-38

Showing the most recent 10 out of 50 publications