Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37ES001060-16S1
Application #
3483746
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1977-05-01
Project End
1991-11-30
Budget Start
1991-09-18
Budget End
1991-11-30
Support Year
16
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Montefiore Medical Center (Bronx, NY)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10467
Finkelstein, Y; Markowitz, M E; Rosen, J F (1998) Low-level lead-induced neurotoxicity in children: an update on central nervous system effects. Brain Res Brain Res Rev 27:168-76
Dowd, T L; Rosen, J F; Gundberg, C M et al. (1994) The displacement of calcium from osteocalcin at submicromolar concentrations of free lead. Biochim Biophys Acta 1226:131-7
Long, G J; Rosen, J F; Schanne, F A (1994) Lead activation of protein kinase C from rat brain. Determination of free calcium, lead, and zinc by 19F NMR. J Biol Chem 269:834-7
Long, G J; Rosen, J F (1994) Lead perturbs 1,25 dihydroxyvitamin D3 modulation of intracellular calcium metabolism in clonal rat osteoblastic (ROS 17/2.8) cells. Life Sci 54:1395-402
Rosen, J F; Crocetti, A F; Balbi, K et al. (1993) Bone lead content assessed by L-line x-ray fluorescence in lead-exposed and non-lead-exposed suburban populations in the United States. Proc Natl Acad Sci U S A 90:2789-92
Schanne, F A; Gupta, R K; Rosen, J F (1992) Lead inhibits 1,25-dihydroxyvitamin D-3 regulation of calcium metabolism in osteoblastic osteosarcoma cells (ROS 17/2.8). Biochim Biophys Acta 1180:187-94
Long, G J; Pounds, J G; Rosen, J F (1992) Lead intoxication alters basal and parathyroid hormone-regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells. Calcif Tissue Int 50:451-8
Rosen, J F (1992) Health effects of lead at low exposure levels. Expert consensus and rationale for lowering the definition of childhood lead poisoning. Am J Dis Child 146:1278-81
Long, G J; Rosen, J F (1992) Lead perturbs epidermal growth factor (EGF) modulation of intracellular calcium metabolism and collagen synthesis in clonal rat osteoblastic (ROS 17/2.8) cells. Toxicol Appl Pharmacol 114:63-70
Long, G J; Rosen, J F; Pounds, J G (1990) Lead impairs the production of osteocalcin by rat osteosarcoma (ROS 17/2.8) cells. Toxicol Appl Pharmacol 106:270-7

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