Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37GM046503-13S1
Application #
6904158
Study Section
Medicinal Chemistry Study Section (MCHA)
Program Officer
Schwab, John M
Project Start
1991-09-01
Project End
2007-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
13
Fiscal Year
2004
Total Cost
$16,800
Indirect Cost
Name
University of Maryland College Park
Department
Chemistry
Type
Schools of Earth Sciences/Natur
DUNS #
790934285
City
College Park
State
MD
Country
United States
Zip Code
20742
Cheng, Qing-Qing; Deng, Yongming; Lankelma, Marianne et al. (2017) Cycloaddition reactions of enoldiazo compounds. Chem Soc Rev 46:5425-5443
Sha, Qiang; Arman, Hadi; Doyle, Michael P (2016) Asymmetric synthesis of 1H-pyrrol-3(2H)-ones from 2,3-diketoesters by combination of aldol condensation with benzilic acid rearrangement. Chem Commun (Camb) 52:108-11
Deng, Yongming; Jing, Changcheng; Zavalij, Peter Y et al. (2015) Hg(OTf)2 Catalyzed Intramolecular 1,4-Addition of Donor-Acceptor Cyclopropenes to Arenes. Org Lett 17:4312-5
Xu, Xinfang; Deng, Yongming; Yim, David N et al. (2015) Enantioselective cis-?-lactam synthesis by intramolecular C-H functionalization from enoldiazoacetamides and derivative donor-acceptor cyclopropenes. Chem Sci 6:2196-2201
Xu, Xinfang; Wang, Xiangbo; Zavalij, Peter Y et al. (2015) Straightforward access to the [3.2.2]nonatriene structural framework via intramolecular cyclopropenation/Buchner reaction/Cope rearrangement cascade. Org Lett 17:790-3
Xu, Xinfang; Doyle, Michael P (2014) The [3 + 3]-cycloaddition alternative for heterocycle syntheses: catalytically generated metalloenolcarbenes as dipolar adducts. Acc Chem Res 47:1396-405
Xu, Xinfang; Zavalij, Peter Y; Hu, Wenhao et al. (2013) Vinylogous reactivity of enol diazoacetates with donor-acceptor substituted hydrazones. Synthesis of substituted pyrazole derivatives. J Org Chem 78:1583-8
Xu, Xichen; Qian, Yu; Zavalij, Peter Y et al. (2013) Highly selective catalyst-dependent competitive 1,2-CýýýC, -OýýýC, and -NýýýC migrations from ýý-methylene-ýý-silyloxy-ýý-amido-ýý-diazoacetates. J Am Chem Soc 135:1244-7
Qian, Yu; Zavalij, Peter J; Hu, Wenhao et al. (2013) Bicyclic pyrazolidinone derivatives from diastereoselective catalytic [3 + 3]-cycloaddition reactions of enoldiazoacetates with azomethine imines. Org Lett 15:1564-7
Xu, Xinfang; Zavalij, Peter Y; Doyle, Michael P (2013) Highly enantioselective dearomatizing formal [3+3] cycloaddition reactions of N-acyliminopyridinium ylides with electrophilic enol carbene intermediates. Angew Chem Int Ed Engl 52:12664-8

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