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Wang, Yingcai; Pinto, Jose Renato; Solis, Raquel Sancho et al. (2012) Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy. J Biol Chem 287:2156-67
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Pinto, Jose Renato; Gomes, Aldrin V; Jones, Michelle A et al. (2012) The functional properties of human slow skeletal troponin T isoforms in cardiac muscle regulation. J Biol Chem 287:37362-70
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Parvatiyar, Michelle S; Landstrom, Andrew P; Figueiredo-Freitas, Cicero et al. (2012) A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation. J Biol Chem 287:31845-55
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Pinto, Jose Renato; Reynaldo, Daniel P; Parvatiyar, Michelle S et al. (2011) Strong cross-bridges potentiate the Ca(2+) affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: a fast kinetic approach. J Biol Chem 286:1005-13
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Midde, K; Dumka, V; Pinto, J R et al. (2011) Myosin cross-bridges do not form precise rigor bonds in hypertrophic heart muscle carrying troponin T mutations. J Mol Cell Cardiol 51:409-18
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Pinto, Jose Renato; Yang, Shi Wei; Hitz, Marc-Phillip et al. (2011) Fetal cardiac troponin isoforms rescue the increased Ca2+ sensitivity produced by a novel double deletion in cardiac troponin T linked to restrictive cardiomyopathy: a clinical, genetic, and functional approach. J Biol Chem 286:20901-12
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Dweck, David; Reynaldo, Daniel P; Pinto, Jose R et al. (2010) A dilated cardiomyopathy troponin C mutation lowers contractile force by reducing strong myosin-actin binding. J Biol Chem 285:17371-9
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Parvatiyar, Michelle S; Pinto, Jose Renato; Liang, Jingsheng et al. (2010) Predicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C. J Biol Chem 285:27785-97
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Parvatiyar, Michelle S; Pinto, Jose Renato; Dweck, David et al. (2010) Cardiac troponin mutations and restrictive cardiomyopathy. J Biomed Biotechnol 2010:350706
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Wen, Yuhui; Xu, Yuanyuan; Wang, Yingcai et al. (2009) Functional effects of a restrictive-cardiomyopathy-linked cardiac troponin I mutation (R145W) in transgenic mice. J Mol Biol 392:1158-67
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