EXCEED THE SPACE PROVIDED. PERFORMANCE SITE(S) (organization, city, state] Johns; Hopkins University School of Medicine Department of Neuroscience 725 N. Wolfe St. Baltimore, Maryland 21205 Name Solomon H. Snyder Johns Hongbo Robert Luo Johns Ming Fang Johns Adolfo Saiardi Johns Eiich;ro Nagata Johns Kim, Paul Johns Xiaocong Li Johns Organization Hopkins School of Medicine Hopkins School of Medicine Hopkins School of Medicine Hopkins School of Medicine Hopkins School of Medicine Hopkins School of Medicine Hopkins School of Medicine Rolejm Proje Principal Investigator Postdoctoral Fellow Postdoctoral Fellow Postdoctoral Fellow Postdoctoral Fellow Graduate Student Graduate Student PHS 39 J(Rev. 4/98) Page 2 BB Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b. ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37MH018501-36
Application #
6818215
Study Section
Special Emphasis Panel (NSS)
Program Officer
Asanuma, Chiiko
Project Start
1985-09-01
Project End
2010-04-30
Budget Start
2005-05-01
Budget End
2006-04-30
Support Year
36
Fiscal Year
2005
Total Cost
$1,178,440
Indirect Cost
Name
Johns Hopkins University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Fu, Chenglai; Tyagi, Richa; Chin, Alfred C et al. (2018) Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1? Degradation. Circ Res 122:457-472
Kornberg, Michael D; Bhargava, Pavan; Kim, Paul M et al. (2018) Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Science 360:449-453
Sbodio, Juan I; Snyder, Solomon H; Paul, Bindu D (2018) Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington's disease. Proc Natl Acad Sci U S A 115:780-785
Paul, Bindu D; Snyder, Solomon H (2018) Gasotransmitter hydrogen sulfide signaling in neuronal health and disease. Biochem Pharmacol 149:101-109
Peng, Ying-Jie; Zhang, Xiuli; Gridina, Anna et al. (2017) Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proc Natl Acad Sci U S A 114:1413-1418
Sbodio, Juan I; Snyder, Solomon H; Paul, Bindu D (2016) Transcriptional control of amino acid homeostasis is disrupted in Huntington's disease. Proc Natl Acad Sci U S A 113:8843-8
Kim, Hyo Jung; Cha, Jiyoung Y; Seok, Jo Woon et al. (2016) Dexras1 links glucocorticoids to insulin-like growth factor-1 signaling in adipogenesis. Sci Rep 6:28648
Choi, Hyong Woo; Tian, Miaoying; Manohar, Murli et al. (2015) Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives. PLoS One 10:e0143447
Paul, Bindu D; Snyder, Solomon H (2015) H2S: A Novel Gasotransmitter that Signals by Sulfhydration. Trends Biochem Sci 40:687-700
Ahmed, Ishrat; Sbodio, Juan I; Harraz, Maged M et al. (2015) Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase. Proc Natl Acad Sci U S A 112:9751-6

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