Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37MH038256-20
Application #
6671440
Study Section
Special Emphasis Panel (NSS)
Program Officer
Asanuma, Chiiko
Project Start
1983-01-01
Project End
2007-02-28
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
20
Fiscal Year
2003
Total Cost
$339,170
Indirect Cost
Name
University of California San Francisco
Department
Pharmacology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Nguyen, Quynh-Anh; Nicoll, Roger A (2018) The GABAA Receptor ? Subunit Is Required for Inhibitory Transmission. Neuron 98:718-725.e3
Horn, Meryl E; Nicoll, Roger A (2018) Somatostatin and parvalbumin inhibitory synapses onto hippocampal pyramidal neurons are regulated by distinct mechanisms. Proc Natl Acad Sci U S A 115:589-594
Ullman, Julie C; Yang, Jing; Sullivan, Michael et al. (2018) A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry. Nat Commun 9:330
Won, Sehoon; Levy, Jon M; Nicoll, Roger A et al. (2017) MAGUKs: multifaceted synaptic organizers. Curr Opin Neurobiol 43:94-101
Won, Sehoon; Incontro, Salvatore; Nicoll, Roger A et al. (2016) PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61. Proc Natl Acad Sci U S A 113:E4736-44
Chen, Xiaobing; Levy, Jonathan M; Hou, Austin et al. (2015) PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density. Proc Natl Acad Sci U S A 112:E6983-92
Herring, Bruce E; Silm, Katlin; Edwards, Robert H et al. (2015) Is Aspartate an Excitatory Neurotransmitter? J Neurosci 35:10168-71
Lovero, Kathryn L; Fukata, Yuko; Granger, Adam J et al. (2015) The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function. Proc Natl Acad Sci U S A 112:E4129-37
Bemben, Michael A; Nguyen, Quynh-Anh; Wang, Tongguang et al. (2015) Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses. Proc Natl Acad Sci U S A 112:2551-6
Levy, Jonathan M; Chen, Xiaobing; Reese, Thomas S et al. (2015) Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss. Neuron 87:534-48

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