Abstract

This proposal aims to utilize recombinant DNA technology to identify the genes encoding species-specific immunoreactive proteins of C. pneumoniae, and to evaluate the utility of the corresponding recombinant antigens for the serologic diagnosis of C. pneumoniae. The long term objective is to develop a novel ELISA and or a blot product. This product will be based on identified species-specific recombinant antigens leading to an inexpensive reliable and easy to interpret serodiagnostic test for human C. pneumoniae infection.

Proposed Commercial Applications

NOT AVAILABLE

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Small Business Technology Transfer (STTR) Grants - Phase I (R41)
Project #
1R41AI044517-01
Application #
2777502
Study Section
Special Emphasis Panel (ZRG5-MBC-1 (01))
Program Officer
Taylor, Christopher E
Project Start
1999-09-30
Project End
2000-12-31
Budget Start
1999-09-30
Budget End
2000-12-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Focus/Mrl, Inc.
Department
Type
DUNS #
City
Cypress
State
CA
Country
United States
Zip Code
90630

  Publications

Campbell, L A; Roberts, S; Inoue, S et al. (2001) Evaluation of Chlamydia pneumoniae 43- and 53-kilodalton recombinant proteins for serodiagnosis by Western Blot. Clin Diagn Lab Immunol 8:1231-3