A device and method is proposed for measuring three-dimensional neutron dose distribution in- phantoms on a real-time basis. This method offers the advantages of neutron detectors which are tissue-equivalent and minimize disturbance to neutron scattering within a tissue-equivalent phantom. By proper selection of high vapor-pressure liquid, microsphere (bubble) diameter and the liquid/gel temperature, the proposed instrument can be used to perform neutron dose distributions within intervals over the energy range from 1 keV to 40 MeV. The proposed instrument is expected to provide linear response over the energy ranges from 1 keV to 100 keV and 60 keV to 40 MeV and be capable of accurately recording dose levels as low as 0.01 cGy. The proposed technique allows individual one-dimensional neutron dosimeter rods to be configured into an array suitable for detailed mapping of neutron dose distribution for use in treatment planning.The proposed Phase I program will include experimental verification of accuracy of detection of neutron dose position. The accuracy of predicting position of neutron-induced bubble formation in superheated liquid dispersions using this technique is expected to be within 1-2 mm.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CA057043-01
Application #
3493085
Study Section
Special Emphasis Panel (SSS (B3))
Project Start
1992-06-23
Project End
1992-11-30
Budget Start
1992-06-23
Budget End
1992-11-30
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Eggers and Associates
Department
Type
DUNS #
City
Dublin
State
OH
Country
United States
Zip Code
43017