In this project we will provide proof-of-principle validation of a handheld, fieldable biosensor specifically for the detection and screening of contaminants in foodstuffs at the various stages of food treatment, preparation and processing. The multi-analyte, multi-application LAI Biosensor has the capability for both qualitative and quantitative measurement, detection and screening of foodborne pathogens and toxins in food. The biosensor operates by sensing direct binding without the requirement for secondary fluorescent reporter molecules, or other intermediate chemical reactions. The results of analytical and simulation analysis of the performance of the biosensor has shown its potential for real-time detection and screening with significantly improved detection sensitivity. The biosensor can be configured as a portable """"""""calculator-sized"""""""" unit with simple operating characteristics. Because of its potential portability, without reliance on supplies the fieldable units would be used in state and local water quality contaminant detection for both testing, process control and event detection. These uses provide a significant market.

Proposed Commercial Applications

We expect that a """"""""real-time"""""""" portable multi-pathogen detection system for direct use in large scale food processing will provide the mechanisms required by the industry to maintain high efficiency at reduced manpower and supply costs. At the same time the turn around time will significantly reduce potential liability attached to contamination events. Other commercial applications include water quality, pathogen contamination detection for mandated municipal and state water quality programs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CA089879-01
Application #
6293431
Study Section
Special Emphasis Panel (ZRG1-SSS-T (01))
Program Officer
Czarra, Allan W
Project Start
2001-08-03
Project End
2002-04-30
Budget Start
2001-08-03
Budget End
2002-04-30
Support Year
1
Fiscal Year
2001
Total Cost
$121,947
Indirect Cost
Name
Loats Associates, Inc.
Department
Type
DUNS #
119697019
City
Westminster
State
MD
Country
United States
Zip Code
21157