Daily use of a sonic toothbrush has been shown to significantly reduce supragingival plaque, subgingival bacterial and periodontal pocket depth. The primary objective of the current application is to further enhance the efficacy of the sonic toothbrush. Laboratory evaluation of various design iterations will be conducted with in vitro assays. This approach may provide high potential for improved oral health, for both the general population and those with periodontal diseases.

Proposed Commercial Applications

This product combined with novel liquid dentifrices may create a major new segment of the currently $1.4 billion/year dentifrice market. More importantly, the product may provide a practical adjunctive therapy for patients with periodontal diseases and may have a major impact in reducing the incidence of periodontal diseases in the general population.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43DE010455-01A1
Application #
2131349
Study Section
Special Emphasis Panel (ZRG4-SOH (03))
Project Start
1995-09-15
Project End
1996-03-14
Budget Start
1995-09-15
Budget End
1996-03-14
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Optiva Corporation
Department
Type
DUNS #
City
Bellevue
State
WA
Country
United States
Zip Code
98005