A novel means of maintaining the sterility of ophthalmic solutions is proposed wherein a membrane type dispenser is employed to provide sterile preservative free solutions. The device protects a sterile solution through the use of a specially treated membrane that prevents the growth of micro organisms from the septic side of the bottle. The proposed dispenser maintains sterility by employing two distinct mechanisms, these being the filtration of pathogens from a solution through physical exclusion, as related to the size of the pores of the membrane. Secondly, and most importantly, pathogens cannot """"""""grow- through"""""""" the membrane because it is chemically treated to be toxic to such pathogens.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43EY010787-01
Application #
2164908
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-09-01
Project End
1995-02-28
Budget Start
1994-09-01
Budget End
1995-02-28
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Biopolymerix, Inc.
Department
Type
DUNS #
City
Tyngsboro
State
MA
Country
United States
Zip Code
01879