A multichannel microelectrode that monitors neurochemical concentrations from many nearby brain sites simultaneously will be highly beneficial to brain researchers. Such a tool will allow scientists both to collect data more efficiently and to study the dynamics of neurochemical gradients during animal behavior within any brain structure.
The aim of the proposed research is to design, develop and evaluate a multichannel microelectrode system for mass production and commercialization to the neuroscience and biomedical communities. This multichannel neurochemical recording system is called """"""""PRONG"""""""" which stands for """"""""Parallel Recording of Neural Groups"""""""". It includes a 24 channel microelectrode and a special connector. The proposed research will modify a working prototype of the PRONG system that has been used to record neural potentials so that it can be used for parallel voltammetry in vivo. The PRONGs will be tested for their sensitivity to dopamine concentration gradients.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43NS025854-01
Application #
3504244
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-01-15
Project End
1988-07-14
Budget Start
1988-01-15
Budget End
1988-07-14
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Network Instruments
Department
Type
DUNS #
City
Brookline
State
MA
Country
United States
Zip Code
02146