Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of genes at the mRNA level in single cells with spatial information preserved. Recent advances now make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al., Nature 2019). With this technology, novel cell types can be discovered in situ and spatial organizations can be directly identified and visualized in brain tissue sections.

Public Health Relevance

Spatial Genomics is developing a transformative technology to profile the transcriptome in single cells in situ. This technology can image gene expression directly in the brain and has many applications to neurodegenerative diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44MH115538-03
Application #
10082281
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Grabb, Margaret C
Project Start
2018-07-01
Project End
2022-08-31
Budget Start
2020-09-04
Budget End
2021-08-31
Support Year
3
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Spatial Genomics, Inc.
Department
Type
DUNS #
080426411
City
Pasadena
State
CA
Country
United States
Zip Code
91107