This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
James A. Shannon Director's Award (R55)
Project #
1R55EY010542-01A1
Application #
2164471
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1994-09-30
Project End
1996-05-31
Budget Start
1994-09-30
Budget End
1996-05-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Plog, Stephanie; Klymiuk, Nikolai; Binder, Stefanie et al. (2015) Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype. PLoS One 10:e0140050
Van Hook, Matthew J; Parmelee, Caitlyn M; Chen, Minghui et al. (2014) Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors. J Gen Physiol 144:357-78
Bennett, Lea D; Hopiavuori, Blake R; Brush, Richard S et al. (2014) Examination of VLC-PUFA-deficient photoreceptor terminals. Invest Ophthalmol Vis Sci 55:4063-72
Cork, Karlene M; Thoreson, Wallace B (2014) Rapid kinetics of endocytosis at rod photoreceptor synapses depends upon endocytic load and calcium. Vis Neurosci 31:227-35
Sim, S L; Szalewski, R J; Johnson, L J et al. (2014) Simultaneous recording of mouse retinal ganglion cells during epiretinal or subretinal stimulation. Vision Res 101:41-50
Van Hook, Matthew J; Thoreson, Wallace B (2014) Endogenous calcium buffering at photoreceptor synaptic terminals in salamander retina. Synapse 68:518-28
Ryskamp, Daniel A; Jo, Andrew O; Frye, Amber M et al. (2014) Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia. J Neurosci 34:15689-700
Van Hook, Matthew J; Thoreson, Wallace B (2013) Simultaneous whole-cell recordings from photoreceptors and second-order neurons in an amphibian retinal slice preparation. J Vis Exp :
Mercer, Aaron J; Thoreson, Wallace B (2013) Tracking quantum dot-tagged calcium channels at vertebrate photoreceptor synapses: retinal slices and dissociated cells. Curr Protoc Neurosci Chapter 2:Unit 2.18
Hanneken, Anne M; Babai, Norbert; Thoreson, Wallace B (2013) Oral proton pump inhibitors disrupt horizontal cell-cone feedback and enhance visual hallucinations in macular degeneration patients. Invest Ophthalmol Vis Sci 54:1485-9

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