Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
High Priority, Short Term Project Award (R56)
Project #
2R56HL070929-07
Application #
7496666
Study Section
Vascular Cell and Molecular Biology Study Section (VCMB)
Program Officer
Barouch, Winifred
Project Start
2002-08-01
Project End
2008-03-31
Budget Start
2007-09-30
Budget End
2008-03-31
Support Year
7
Fiscal Year
2007
Total Cost
$371,250
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Kim, Young-Rae; Kim, Cuk-Seong; Naqvi, Asma et al. (2012) Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction. Am J Physiol Heart Circ Physiol 303:H189-96
Irani, Kaikobad (2011) Crippling of Krüppel (-like factor 2) by bad flow portends a miRky day for endothelial function. Circulation 124:541-3
Kumar, Ajay; Kim, Cuk-Seong; Hoffman, Timothy A et al. (2011) p53 impairs endothelial function by transcriptionally repressing Kruppel-Like Factor 2. Arterioscler Thromb Vasc Biol 31:133-41
Kim, Cuk-Seong; Kim, Young-Rae; Naqvi, Asma et al. (2011) Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc. Cardiovasc Res 92:466-75
Jung, Saet-Byel; Kim, Cuk-Seong; Naqvi, Asma et al. (2010) Histone deacetylase 3 antagonizes aspirin-stimulated endothelial nitric oxide production by reversing aspirin-induced lysine acetylation of endothelial nitric oxide synthase. Circ Res 107:877-87