Abstract

The primary goal of the research outlined here is to provide greater insight into the relationships between sleep and health and in so doing, to clarify theoretical assumptions on the manner by which sleep affects behavior. Specifically seven studies have been proposed. Four of these studies are designed to promote a greater understanding of certain conditions which may be disruptive to sleep (e.g., smoking and stressful experience) or disorder (i.e., bruxism) that occur primarily during sleep. The remaining three studies are designed to clarify the relationships between REM sleep deprivation and aggression. Four of these studies use animals (rats) as subjects and three call for the use of collection of daily diary data from large groups of adults over an extended period of time. In addition to the scientific value and the possible health-related implications of the data, these studies have been selected to maximize the research skills of the students who will be involved as research assistants with them.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM008192-13
Application #
3841710
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
San Jose State University
Department
Type
DUNS #
City
San Jose
State
CA
Country
United States
Zip Code
95112

  Publications

Saleh, Nidal; Moore 2nd, Barry; Srebro, Monika et al. (2015) Acid/base-triggered switching of circularly polarized luminescence and electronic circular dichroism in organic and organometallic helicenes. Chemistry 21:1673-81
Saleh, Nidal; Srebro, Monika; Reynaldo, Thibault et al. (2015) enantio-Enriched CPL-active helicene-bipyridine-rhenium complexes. Chem Commun (Camb) 51:3754-7
Zhang, Xiao-Peng; Chang, Victoria Y; Liu, Jian et al. (2015) Potential switchable circularly polarized luminescence from chiral cyclometalated platinum(II) complexes. Inorg Chem 54:143-52
Sundar, M Shyam; Talele, Harish R; Mande, Hemant M et al. (2014) Synthesis of enantiomerically pure helicene like bis-oxazines from atropisomeric 7,7'-dihydroxy BINOL: Preliminary measurements of the circularly polarized luminescence. Tetrahedron Lett 55:1760-1764
Sánchez-Carnerero, Esther M; Moreno, Florencio; Maroto, Beatriz L et al. (2014) Circularly polarized luminescence by visible-light absorption in a chiral O-BODIPY dye: unprecedented design of CPL organic molecules from achiral chromophores. J Am Chem Soc 136:3346-9
Shen, Chengshuo; Anger, Emmanuel; Srebro, Monika et al. (2014) Straightforward access to mono- and bis-cycloplatinated helicenes that display circularly polarized phosphorescence using crystallization resolution methods. Chem Sci 5:1915-1927
Tohgha, Urice; Deol, Kirandeep K; Porter, Ashlin G et al. (2013) Ligand induced circular dichroism and circularly polarized luminescence in CdSe quantum dots. ACS Nano 7:11094-102
Brunet, Ernesto; Jimenez, Laura; de Victoria-Rodriguez, Maria et al. (2013) The use of lanthanide luminescence as a reporter in the solid state: Desymmetrization of the prochiral layers of ýý-zirconium phosphate/phosphonate and circularly polarized luminescence. Microporous Mesoporous Mater 169:222-234
Bozoklu, Gulay; Gateau, Christelle; Imbert, Daniel et al. (2012) Metal-controlled diastereoselective self-assembly and circularly polarized luminescence of a chiral heptanuclear europium wheel. J Am Chem Soc 134:8372-5
Carey, Clayton M; Bueno, Raymund; Gutierrez, Daniel A et al. (2012) Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28. Toxicon 59:241-8

Showing the most recent 10 out of 47 publications