The HUC Biomedical Research Improvement Program will initiate strong biomedical research efforts among faculty members at the Humacao University College. It will provide the opportunity to faculty members from the Marine Biology, Chemistry and Mathematics Departments to improve their research participation and productivity in areas related to the biomedicine. In order to accomplish this objective, funds are requested for summer salaries and to purchase the needed ewuipment and supplies. Travel funds are also requested. The Program will also stimulate the participation of other faculty members in biomedical research through the accomplishments of our MBS faculty participants. The Program will also serve as a means to get undergraduate science students (sophomore, junior and/or senior) involved in actual scientific research in biomedical sciences; therefore stimulating their interest in graduate biomedical research. Eight students, with moderate to excellent academic qualifications, will be selected as MBS participants. This application involves four projects. One of them is in the area of physiology (thyroid hormone activity). Another will be in blood flow modeling. A chemistry project will deal with the calculation of binding constants between vanadium containing ligands and other biochemical species and the relation of these constants with the vascular system activity. Finally, a project involving the determination of the thermodynamic parameters controlling the stabilities of semiquinones is also proposed. This Biomedical Research Program will commit the Humacao University College to improve its research capabilities by creating an appropiate setting for biomedical research activities.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
2S06GM008216-08
Application #
3513533
Study Section
Minority Programs Review Committee (MPRC)
Project Start
1983-09-01
Project End
1994-08-31
Budget Start
1990-09-24
Budget End
1991-08-31
Support Year
8
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Puerto Rico at Humacao
Department
Type
Schools of Arts and Sciences
DUNS #
City
Humacao
State
PR
Country
United States
Zip Code
00791
Gawronski, Katerina A B; Kim, Junhyong (2017) Single cell transcriptomics of noncoding RNAs and their cell-specificity. Wiley Interdiscip Rev RNA 8:
Falk, Samantha J; Lee, Jaehyoun; Sekulic, Nikolina et al. (2016) CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres. Nat Struct Mol Biol 23:204-208
Falk, Samantha J; Guo, Lucie Y; Sekulic, Nikolina et al. (2015) Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science 348:699-703
Sanchez-Cruz, Pedro; Santos, Areli; Diaz, Stephany et al. (2014) Metal-independent reduction of hydrogen peroxide by semiquinones. Chem Res Toxicol 27:1380-6
Piñero-Santiago, Luis E; García, Carmelo; Lhiaubet-Vallet, Virginie et al. (2013) Photooxidation mechanism of levomepromazine in different solvents. Photochem Photobiol 89:1479-89
Bryant, Jessica M; Meyer-Ficca, Mirella L; Dang, Vanessa M et al. (2013) Separation of spermatogenic cell types using STA-PUT velocity sedimentation. J Vis Exp :
Castillo, Betzaida; Bromberg, Lev; López, Xaira et al. (2012) Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles. J Drug Deliv 2012:218940
Sanchez-Cruz, Pedro; Dejesus-Andino, Francisco; Alegria, Antonio E (2012) Roles of hydrophilicities and hydrophobicities of dye and sacrificial electron donor on the photochemical pathway. J Photochem Photobiol A Chem 236:54-60
Stepanenko, Viatcheslav; de Jesús, Melvin; Garcia, Carmelo et al. (2012) Synthesis and stability of new spiroaminoborate esters. Tetrahedron Lett 53:910-913
Bansal, Vibha; Delgado, Yamixa; Legault, Marc et al. (2012) Low operational stability of enzymes in dry organic solvents: changes in the active site might affect catalysis. Molecules 17:1870-82

Showing the most recent 10 out of 65 publications