The SCORE Program at Cal Poly Pomona was established in June 2000 and renewed in September 2004 to significantly improve the research capabilities of the University with the ultimate objective of increasing the number of underrepresented minority students who are motivated to pursue careers as biomedical scientists. To achieve these ends the program funds high quality research leading to peer-reviewed publications and strengthens the infrastructure for scientific research. The existing program includes six subprojects involving faculty with strong, demonstrable commitments to research and to graduate and undergraduate education. The currently funded program is interdisciplinary, involving faculty from three academic departments in two different colleges. The seven projects included in this supplement will add three new departments (Animal and Veterinary Sciences, Kinesiology, Psychology and Sociology), the latter two being from a College not currently represented in our program. These projects also include three female investigators, one of them (Dr. Floriano) a Latina. The proposed SCORE projects significantly expand the range of research projects to include organic chemistry (Dr. Liu), two aspects of the health of the local underrepresented minority community (Drs. Algert and Liang), psychological aspects of health care delivery to different ethnic groups (Dr. Alvarado), molecular physiology (Dr. Gruber), biomechanics (Dr. Wickler), and bioinformatics (Dr. Floriano). ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
3S06GM053933-10S1
Application #
7138562
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Singh, Shiva P
Project Start
1998-04-01
Project End
2008-08-31
Budget Start
2006-09-01
Budget End
2007-08-31
Support Year
10
Fiscal Year
2006
Total Cost
$423,461
Indirect Cost
Name
California State Polytechnic University Pomona
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
028929438
City
Pomona
State
CA
Country
United States
Zip Code
91768
Dadgar, Saedeh; Floriano, Wely B (2015) Systematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A). Mol Cell Probes 29:135-43
Dadgar, Saedeh; Ramjan, Zack; Floriano, Wely B (2013) Paclitaxel is an inhibitor and its boron dipyrromethene derivative is a fluorescent recognition agent for botulinum neurotoxin subtype A. J Med Chem 56:2791-803
Chew, Tina W; Jiang, Xinyin; Yan, Jian et al. (2011) Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr 141:1475-81
Liang, M T C; Braun, W; Bassin, S L et al. (2011) Effect of high-impact aerobics and strength training on BMD in young women aged 20-35 years. Int J Sports Med 32:100-8
Yan, Jian; Wang, Wei; Gregory 3rd, Jesse F et al. (2011) MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr 93:348-55
Shin, William; Yan, Jian; Abratte, Christian M et al. (2010) Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men. J Nutr 140:975-80
Austin, Misa U; Liau, Wei-Siang; Balamurugan, Krishnaswamy et al. (2010) Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. BMC Dev Biol 10:46
Caudill, Marie A; Dellschaft, Neele; Solis, Claudia et al. (2009) Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr 139:727-33
Ivanov, Alexandre; Nash-Barboza, Susan; Hinkis, Sabrina et al. (2009) Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted. J Am Diet Assoc 109:313-8
Lee, Justine; Bernard, Steven; Liu, Xiao-Chuan (2009) Nanostructured Biomimetic Catalysts for Asymmetric Hydrogenation of Enamides using Molecular Imprinting Technology. React Funct Polym 69:650-654

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