Abstract

The goal of this proposed research is to test hypothesis pertaining to mitochondrial DNA (mtDNA) genetics in the aftermath of recent genetic bottleneck ing two California populations of yellowfin goby, a marine fish. The hypothesis is that the ratio of single-observation (i.e., singleton) mtDNAs to total distinct mtDNA observed in a population sample, is a general indicator of recent population-genetic bottlenecking. To test, I will study and compare the mtDNA and nuclear allelic genetics of two California populations of yellowfish goby, a recent colonizer from Asia, with that of a native (control) species in California plus that of a yellowfish goby population in China. Control region sequences of about 900 pairs from 50 specimen mtDNAs, plus allele frequencies at 15 microsatellite loci, from each population in each of three years will constitute the genetic data. This new approach will potentially yield new information of importance to society on what controls genetic and species diversity over relatively short time scales by providing a way to recognize contemporary, syntopic genetic bottlenecks in natural populations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM063119-02
Application #
6659297
Study Section
Minority Programs Review Committee (MPRC)
Project Start
2002-09-30
Project End
2003-09-29
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
California State University Long Beach
Department
Type
DUNS #
City
Long Beach
State
CA
Country
United States
Zip Code
90840

  Publications

Nishiya, Casey T; Boxx, Gayle M; Robison, Kerry et al. (2016) Influence of IgG Subclass on Human Antimannan Antibody-Mediated Resistance to Hematogenously Disseminated Candidiasis in Mice. Infect Immun 84:386-94
Valinluck, Michael; Woraratanadharm, Tad; Lu, Ching-yu et al. (2014) The cell end marker Tea4 regulates morphogenesis and pathogenicity in the basidiomycete fungus Ustilago maydis. Fungal Genet Biol 66:54-68
Nelson, O Lynne; Rourke, Bryan C (2013) Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction. J Exp Biol 216:4678-90
Kamei, Ayako; Hauser, Paul S; Beckstead, Jennifer A et al. (2012) Expressed protein ligation-mediated template protein extension. Protein Expr Purif 83:113-6
Nowell, Megan M; Choi, Hyung; Rourke, Bryan C (2011) Muscle plasticity in hibernating ground squirrels (Spermophilus lateralis) is induced by seasonal, but not low-temperature, mechanisms. J Comp Physiol B 181:147-64
Aoi, Mikio C; Rourke, Bryan C (2011) Interspecific and intragenic differences in codon usage bias among vertebrate myosin heavy-chain genes. J Mol Evol 73:74-93
Gharakhanian, Editte; Chima-Okereke, Onyinyechi; Olson, Daniel K et al. (2011) env1 Mutant of VPS35 gene exhibits unique protein localization and processing phenotype at Golgi and lysosomal vacuole in Saccharomyces cerevisiae. Mol Cell Biochem 346:187-95
Barrows, N D; Nelson, O L; Robbins, C T et al. (2011) Increased cardiac alpha-myosin heavy chain in left atria and decreased myocardial insulin-like growth factor (Igf-I) expression accompany low heart rate in hibernating grizzly bears. Physiol Biochem Zool 84:1-17
Shahed, Asha; Young, Kelly A (2011) Intraovarian expression of GnRH-1 and gonadotropin mRNA and protein levels in Siberian hamsters during the estrus cycle and photoperiod induced regression/recrudescence. Gen Comp Endocrinol 170:356-64
Valinluck, Michael; Ahlgren, Sara; Sawada, Mizuho et al. (2010) Role of the nuclear migration protein Lis1 in cell morphogenesis in Ustilago maydis. Mycologia 102:493-512

Showing the most recent 10 out of 81 publications