Institutional Development - Harned Hall is presently being renovated to serve primarily as a research facility at Tennessee State University. The growth of research which resulted in this major renovation by the State was largey due to MBRS funding. Research Progress - Six projects are being conducted in the areas of enzymology, pharmacology, morphogenesis, toxicology, biofeedback, and neurobiology. The problems being studied include a) characterization of mammalian phosphodiesterase, (b) neurotransmission in the horseshoe crab, c) toxic and developmental effects of PCBs, d) drug binding kinetics (specifically the binding kinetics of antimetabolites to DNA), e) biofeedback mediated control of ambient skin temperature in humans, f) CNS depressants, their effects and interactions with other chemicals, and g) electron microscopic studies of the nervous system of Limulus. Student Training - Training of students in all facets of the program will continue with emphasis being placed on improving the quality of our M.S. graduates. Publications - We plan to continue to build upon a good publication record of our PIs during the current budget year.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06RR008092-13
Application #
3513917
Study Section
General Research Support Program Advisory Committee (GRS)
Project Start
1979-03-01
Project End
1989-02-28
Budget Start
1986-03-01
Budget End
1987-02-28
Support Year
13
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Tennessee State University
Department
Type
Schools of Arts and Sciences
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37209
Cummings, Sherry M; Neff, James Alan; Husaini, Baqar A (2003) Functional impairment as a predictor of depressive symptomatology: the role of race, religiosity, and social support. Health Soc Work 28:23-32
Husaini, B A; Blasi, A J; Miller, O (1999) Does public and private religiosity have a moderating effect on depression? A bi-racial study of elders in the American South. Int J Aging Hum Dev 48:63-72
Husaini, B A (1997) Predictors of depression among the elderly: racial differences over time. Am J Orthopsychiatry 67:48-58
Linn, J G; Monnig, R L; Cain, V A et al. (1993) Stage of illness, level of HIV symptoms, sense of coherence and psychological functioning in clients of community-based AIDS counseling centers. J Assoc Nurses AIDS Care 4:24-32
Linn, J G; Lewis, F M; Cain, V A et al. (1993) HIV-illness, social support, sense of coherence, and psychosocial well-being in a sample of help-seeking adults. AIDS Educ Prev 5:254-62
Barrett, H R; Tucker, J H; Grier, W P et al. (1988) Response variability as a predictor of skin temperature biofeedback performance. Int J Neurosci 42:45-9
Pollard Jr, S; Adams, J A (1988) Artificially induced metamorphosis acetone in Acris gryllus. Arch Environ Contam Toxicol 17:419-28
Herring, C O; Adams, J A; Wilson, B A et al. (1988) Dose-response studies using ethylene dibromide (EDB) in Hydra oligactis. Bull Environ Contam Toxicol 40:35-40
Barrett, H R; Streets, T M; Tucker, J H et al. (1987) Skin temperature biofeedback for multiple sessions with monetary incentives. Percept Mot Skills 65:139-46
Parker, G R; Lin, Y M (1987) Isolation from lugworm (Arenicola cristata) of four proteases that activate cyclic AMP phosphodiesterase. Comp Biochem Physiol B 88:349-57

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