Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
3S06RR008111-16S2
Application #
3513979
Study Section
General Research Support Program Advisory Committee (GRS)
Project Start
1978-06-01
Project End
1989-02-28
Budget Start
1987-09-01
Budget End
1989-02-28
Support Year
16
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Florida Agricultural and Mechanical University
Department
Type
Schools of Pharmacy
DUNS #
City
Tallahassee
State
FL
Country
United States
Zip Code
32307
Errahali, Younes J; Taka, Equar; Abonyo, Barack O et al. (2009) CCL26-targeted siRNA treatment of alveolar type II cells decreases expression of CCR3-binding chemokines and reduces eosinophil migration: implications in asthma therapy. J Interferon Cytokine Res 29:227-39
Taka, Equar; Errahali, Younes J; Abonyo, Barack O et al. (2008) Post-transcriptional silencing of CCR3 downregulates IL-4 stimulated release of eotaxin-3 (CCL26) and other CCR3 ligands in alveolar type II cells. Cytokine 44:342-51
You, Zhengqing; Lee, Henry Young (2006) New AZT conjugates as potent anti-HIV agents. Nucleosides Nucleotides Nucleic Acids 25:37-54
You, Zhengqing; Mian, A Moshin; Agarwal, Ram P et al. (2003) Synthesis, anti-HIV, and cytotoxic activity of new AZT conjugates of steroid acids. Nucleosides Nucleotides Nucleic Acids 22:2049-60
Badewa, A P; Heiman, A S (2003) Inhibition of CCL11, CCL24, and CCL26-induced degranulation in HL-60 eosinophilic cells by specific inhibitors of MEK1/MEK2, p38 MAP kinase, and PI 3-kinase. Immunopharmacol Immunotoxicol 25:145-57
Ko, Dong-Hoon; Heiman, Ann S; Hudson, Charles E et al. (2002) New steroidal antiinflammatory antedrugs: Methyl 3,20-dioxo-9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-1,4-pregnadiene-16 alpha-carboxylate and its 21-O-acyl derivatives. Steroids 67:211-9
Lee, Henry J; Cooperwood, John S; You, Zhengqing et al. (2002) Prodrug and antedrug: two diametrical approaches in designing safer drugs. Arch Pharm Res 25:111-36
Ko, D; Heiman, A S; Chen, M et al. (2000) New steroidal anti-inflammatory antedrugs: methyl 21-desoxy-21-chloro-11beta,17alpha-dihydroxy-3,20-dioxo-1, 4-pregnadiene-16alpha-carboxylate, methyl 21-desoxy-21-chloro-11beta-hydroxy-3,20-dioxo-1, 4-pregnadiene-16alpha-carboxylate, and their 9alpha-flu Steroids 65:210-8
Lee, H J; Ko, D H (1999) A novel approach to the discovery of non-systemic anti-inflammatory steroids;antedrug. Arch Pharm Res 22:279-87
Lee, H J; You, Z; Ko, D H et al. (1998) New steroidal antiinflammatory agents: prednisolone derivatives with an isoxazoline fusion at the 16- and 17-carbons and an alkyl carboxylate at the 16 alpha-position. Drugs Exp Clin Res 24:57-66

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