This application seeks funding to upgrade the console of our 4 Tesla human MRI/MRS system located in the CMRR. This 4 Tesla instrument currently runs with a ~9 year old Varian Inova console and currently limits our ability to implement advanced coils (transmit and receive arrays), pulse sequences, and acquisition methods and to achieve optimal data quality in imaging and spectroscopy applications. The Upgrade requested is to replace the existing console with the new Varian Direct Drive console which has uniquely important new capabilities (specifically, 16 receive and 8 transmit channels) and a myriad of significant performance improvements. The multiple receive and transmit channels are the most critical new capabilities sought in this upgrade. This high field MR system is essential to research projects being conducted within our existing P41 Biotechnology Research Resource (RR08079) and the MR CORE of our GCRC (RR00400), as well as to a large number of basic and clinical research projects funded by R01 and other grants. ? ? ?
Seaquist, Elizabeth R; Moheet, Amir; Kumar, Anjali et al. (2017) Hypothalamic Glucose Transport in Humans During Experimentally Induced Hypoglycemia-Associated Autonomic Failure. J Clin Endocrinol Metab 102:3571-3580 |
Lu, Ming; Zhu, Xiao-Hong; Chen, Wei (2016) In vivo (31) P MRS assessment of intracellular NAD metabolites and NAD(+) /NADH redox state in human brain at 4 T. NMR Biomed 29:1010-7 |
Sohn, Sung-Min; Vaughan, J Thomas; Lagore, Russell L et al. (2016) In vivo MR imaging with simultaneous RF transmission and reception. Magn Reson Med 76:1932-1938 |
Zhang, Jinjin; Idiyatullin, Djaudat; Corum, Curtis A et al. (2016) Gradient-modulated SWIFT. Magn Reson Med 75:537-46 |
Jang, Albert; Kobayashi, Naoharu; Moeller, Steen et al. (2016) 2D Pulses using spatially dependent frequency sweeping. Magn Reson Med 76:1364-1374 |
Öz, Gülin; DiNuzzo, Mauro; Kumar, Anjali et al. (2015) Revisiting Glycogen Content in the Human Brain. Neurochem Res 40:2473-81 |
Satzer, David; DiBartolomeo, Christina; Ritchie, Michael M et al. (2015) Assessment of dysmyelination with RAFFn MRI: application to murine MPS I. PLoS One 10:e0116788 |
Corum, Curtis A; Benson, John C; Idiyatullin, Djaudat et al. (2015) High-spatial- and high-temporal-resolution dynamic contrast-enhanced MR breast imaging with sweep imaging with Fourier transformation: a pilot study. Radiology 274:540-7 |
Idiyatullin, Djaudat; Corum, Curtis A; Garwood, Michael (2015) Multi-Band-SWIFT. J Magn Reson 251:19-25 |
Liimatainen, Timo; Hakkarainen, Hanne; Mangia, Silvia et al. (2015) MRI contrasts in high rank rotating frames. Magn Reson Med 73:254-62 |
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