Morehouse School of Medicines overall strategic goal is to increase the critical mass of talented research faculty pursuing health disparities research augment the pipeline of minority students/fellows pursuing research training in biomedical, clinical and behavioral sciences, and provide the infrastructure needed for investigators to achieve national recognition for their scientific discoveries and translation of new knowledge into community solutions and improved patient care for minorities. The goal of the 5-Year Endowment Strategic Plan is to support personalized prevention and intervention research through the translational continuum of basic science, clinical, and community-based research to move discoveries from the laboratory more rapidly into clinical applications and into widespread use in office settings and in the community. To this end, we will build capacity in Molecular Genetics Research, Clinical Research, and Community-based Prevention Research Infrastructure that will support the following objectives: I) Enhance the basic (and translational research infrastructure for utilizing molecular (genomic, proteomic, and metabolomics) diagnostics and evidence-based, rationale design of therapies and technologies to reduce health disparities;II) Expand the critical mass of talented clinical investigators capable of accelerating translational science in the health disparity research focus areas related to: cancer, neuroscience/stroke, women's health and cardio-metabolic disorders; III) Conduct community-based and public health informatics research to further define and understand the epidemiology of racial and ethnic health disparities and to develop innovative approaches to addressing cancer, neuroscience/stroke and cardiovascular disparities at the population level;and IV) Build a perpetual resource that will enable MSM to continually support growth and development in the areas of cancer, women's health, neuroscience/stroke and cardiovascular disorders.

Public Health Relevance

African Americans have the highest mortality rates from all major causes of death (cancer, diabetes, stroke, heart disease, AIDS). This project will seek to reduce these disparities by building research capacity for personalized clinical and community prevention strategies.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research and Institutional Resources Health Disparities Endowment Grants -Capacity Building (S21)
Project #
2S21MD000101-11
Application #
8308878
Study Section
Special Emphasis Panel (ZMD1-RN (04))
Program Officer
Stinson, Nathaniel
Project Start
2001-09-30
Project End
2016-08-31
Budget Start
2011-09-19
Budget End
2012-08-31
Support Year
11
Fiscal Year
2011
Total Cost
$5,000,000
Indirect Cost
Name
Morehouse School of Medicine
Department
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Owino, Sharon; Sánchez-Bretaño, Aida; Tchio, Cynthia et al. (2018) Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity. J Pineal Res 64:
Augello, Catherine J; Noll, Jessica M; Distel, Timothy J et al. (2018) Identification of novel blood biomarker panels to detect ischemic stroke in patients and their responsiveness to therapeutic intervention. Brain Res 1698:161-169
Huang, Yan; Leng, Tian-Dong; Inoue, Koichi et al. (2018) TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. J Biol Chem 293:14393-14406
Akintobi, Tabia Henry; Hoffman, LaShawn M; McAllister, Calvin et al. (2018) Assessing the Oral Health Needs of African American Men in Low-Income, Urban Communities. Am J Mens Health 12:326-337
Anyanwu, Samuel I; Doherty, Akins; Powell, Michael D et al. (2018) Detection of HIV-1 and Human Proteins in Urinary Extracellular Vesicles from HIV+ Patients. Adv Virol 2018:7863412
Vann, Kiara T; Xiong, Zhi-Gang (2018) Acid-sensing ion channel 1 contributes to normal olfactory function. Behav Brain Res 337:246-251
Gaglioti, Anne H; Xu, Junjun; Rollins, Latrice et al. (2018) Neighborhood Environmental Health and Premature Death From Cardiovascular Disease. Prev Chronic Dis 15:E17
Cooper, Dexter L; Zellner-Lawrence, Tiffany; Mubasher, Mohamed et al. (2018) Examining HPV Awareness, Sexual Behavior, and Intent to Receive the HPV Vaccine Among Racial/Ethnic Male College Students 18-27 years. Am J Mens Health 12:1966-1975
Piano, Ilaria; Baba, Kenkichi; Claudia Gargini et al. (2018) Heteromeric MT1/MT2 melatonin receptors modulate the scotopic electroretinogram via PKC? in mice. Exp Eye Res 177:50-54
Akintobi, Tabia Henry; Lockamy, Elise; Goodin, Lisa et al. (2018) Processes and Outcomes of a Community-Based Participatory Research-Driven Health Needs Assessment: A Tool for Moving Health Disparity Reporting to Evidence-Based Action. Prog Community Health Partnersh 12:139-147

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