The aging of the United States population highlights the need for increased interdisciplinary research on diseases and disabilities that affect older persons. The objective of years 21 ? 25 of this successful program is to continue training 5 pre- and 2 postdoctoral fellows to conduct independent and original research in the epidemiology of aging, with an emphasis on the prevention of late life disability and functional decline and the maximization of function in those with existing disabilities and disabling conditions. The program emphasizes four broad substantive areas in which program faculty have gerontologic research experience and are conducting ongoing projects: musculoskeletal epidemiology; neuroepidemiology; genetic epidemiology; and pharmacoepidemiology. The program prepares trainees to: 1) contribute to an interdisciplinary research team under the supervision of a primary mentor expert in the epidemiology of aging and secondary mentors expert in epidemiology methods and/or biostatistics, gerontology and content areas relevant to trainee research; 2) develop a research question, articulate hypotheses, and design and perform an epidemiologic study to address hypotheses; 3) become expert in at least one substantive area relevant to functional decline and the maximization of function in those with disabilities and disabling conditions; 4) demonstrate excellence in conducting independent, innovative research; 5) gain experience presenting research results; 6) master a core curriculum in epidemiology and biostatistics; 7) be knowledgeable about basic biological and psychosocial processes of aging; 8) master principles of responsible conduct of research; and 9) be prepared for transition to a research career in academia, government, industry or non-profit sector using capabilities in the epidemiology of aging. The program is located within the Department of Epidemiology and Public Health (EPH) of the University of Maryland School of Medicine. Major program strengths include: 1) availability of core epidemiology of aging faculty, and faculty expert in gerontology, epidemiology, biostatistics, and substantive areas that are focus of program; 2) interdisciplinary training and research opportunities in aging and related areas; 3) graduate training opportunities including advanced coursework through the Doctoral Programs in Epidemiology and Human Genetics, Gerontology, and Pharmaceutical Health Services Research; and 4) ability to capitalize on Baltimore/Washington corridor to leverage resources across multiple domains (academia, government, industry, and non-profit). We expect the training program, with its team of dedicated faculty, will continue to serve trainees in launching successful careers as leaders in the epidemiology of aging. The program director is recognized for his leadership nationally and within the University of Maryland; as such, he is in an excellent position to foster the development of trainees through participation in interdisciplinary research programs locally and nationally. Leaders of the Doctoral Programs Epidemiology and Human Genetics and in Gerontology will serve as program associate directors.

Public Health Relevance

The increasing life span is leading to greater numbers of older persons in the population. This training program is designed to prepare outstanding scientists to pursue topics that are relevant for understanding the health and functional status of an aging population, preventing the functional declines and disabilities that often accompany becoming older, and maximizing function in those with existing disabilities and disabling conditions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AG000262-23
Application #
9941005
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Eldadah, Basil A
Project Start
1998-05-01
Project End
2023-04-30
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
23
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Salimi, Shabnam; Shardell, Michelle D; Seliger, Stephen L et al. (2018) Inflammation and Trajectory of Renal Function in Community-Dwelling Older Adults. J Am Geriatr Soc 66:804-811
Gaitonde, Priyanka; Bozzi, Laura M; Shaya, Fadia T (2018) Factors associated with use of disease modifying agents for rheumatoid arthritis in the National Hospital and Ambulatory Medical Care Survey. Semin Arthritis Rheum 47:649-653
Khokhar, Bilal; Simoni-Wastila, Linda; Slejko, Julia F et al. (2018) Mortality and Associated Morbidities Following Traumatic Brain Injury in Older Medicare Statin Users. J Head Trauma Rehabil 33:E68-E76
Sarnowski, ChloƩ; Satizabal, Claudia L; DeCarli, Charles et al. (2018) Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology 90:e188-e196
Rathbun, A M; Magaziner, J; Shardell, M D et al. (2018) Older men who sustain a hip fracture experience greater declines in bone mineral density at the contralateral hip than non-fractured comparators. Osteoporos Int 29:365-373
Choi, Soo Youn; Lim, Sun Woo; Salimi, Shabnam et al. (2018) Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury. J Am Soc Nephrol 29:492-504
Yimgang, Doris P; Sorkin, John D; Evans, Charles F et al. (2018) Angiotensin converting enzyme inhibitors and interstage failure in infants with hypoplastic left heart syndrome. Congenit Heart Dis 13:533-540
Salimi, Shabnam; Shardell, Michelle; Miller, Ram et al. (2018) Soluble Tumor Necrosis Factor Alpha Receptor 1, Bone Resorption, and Bone Mineral Density in the Year Following Hip Fractures: The Baltimore Hip Studies. J Bone Miner Res 33:1649-1656
Rathbun, Alan M; Stuart, Elizabeth A; Shardell, Michelle et al. (2018) Dynamic Effects of Depressive Symptoms on Osteoarthritis Knee Pain. Arthritis Care Res (Hoboken) 70:80-88
Rathbun, Alan M; Shardell, Michelle D; Stuart, Elizabeth A et al. (2018) Persistence of depressive symptoms and gait speed recovery in older adults after hip fracture. Int J Geriatr Psychiatry 33:875-882

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