Program Director/Principal Investigator (Last, First, Middle): Schooley, Robert T. This application requests a renewal of support for the UCSD ?Research in Infectious Disease? T32 Training Grant. The program, now in its 36th year, supports the career development of physician scientists who wish to pursue research training in infectious diseases and microbiology. We are requesting five years of ongoing support for the training of six postdoctoral trainees per year. The training program seeks to recruit a diverse group of trainees who have completed residencies in internal medicine or pediatrics and the first year of clinical training required for board certification in Adult or Pediatric Infectious Diseases. The goal of the T32 is to recruit trainees who wish to pursue rigorous research training that will place them on the pathway to productive, independent research careers. Because of the complexity of contemporary biomedical research and the highly competitive funding environment (especially for early career research scientists), we have extended the average duration of research support for our trainees to three years although the duration ranges from 2 ? 4 years. Based on an assessment of interests of potential trainees and of career development opportunities, the program has continued to evolve from the heavy focus on traditional ?wet lab? research in prior years to include patient oriented and global health research. Although the program is organized into three tracks (Microbial Pathogenesis, Patient Oriented and Global Health Research Training Tracks), multidisciplinary, multi-track training is the hallmark of the training program. The high level of commitment to each trainee in terms of training duration and intensity, coupled with the multidisciplinary character of the training experience has attracted outstanding applicants and has enabled them to be extremely successful in progressing to the next stages of development of careers as physician scientists. Based on a recently completed strategic planning process, we have put plans into place that we believe will allow the program to build on its strengths as we recruit additional faculty with new talents and skills, to strengthen our mentoring programs and to enhance our highly collaborative research environment. The overarching goal of the training program remains to prepare the next generation of physician scientists for highly productive careers in biomedical research with local, national and international impacts.

Public Health Relevance

Schooley, Robert T. This application entitled ?Research Training in Infectious Diseases? seeks a 5-year extension of support for the training of physician scientists in biomedical research related to infectious diseases and microbiology. The program emphasizes multidisciplinary research in the areas of microbial pathogenesis, patient oriented biomedical research and global health. We seek to recruit highly motivated physicians who have completed training in internal medicine or pediatrics and to expose them to the contemporary research techniques required to provide them with the broad skills necessary to pursue careers as productive, socially responsible, collaborative biomedical research scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007036-40
Application #
9964624
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Coomes, Stephanie
Project Start
1976-07-01
Project End
2021-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
40
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Martin, T C S; Abdelmalek, J; Yee, B et al. (2018) Pasteurella multocida line infection: a case report and review of literature. BMC Infect Dis 18:420
Promer, Katherine; Karris, Maile Y (2018) Current Treatment Options for HIV Elite Controllers: a Review. Curr Treat Options Infect Dis 10:302-309
Horton, Lucy E; Mehta, Sanjay R; Aganovic, Lejla et al. (2018) Actinotignum schaalii Infection: A Clandestine Cause of Sterile Pyuria? Open Forum Infect Dis 5:ofy015
Martin, Thomas C S; Vinetz, Joseph M (2018) Asymptomatic Plasmodium vivax parasitaemia in the low-transmission setting: the role for a population-based transmission-blocking vaccine for malaria elimination. Malar J 17:89
Cowell, Annie N; Istvan, Eva S; Lukens, Amanda K et al. (2018) Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science 359:191-199
Oldstone, Michael B A; Ware, Brian C; Horton, Lucy E et al. (2018) Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics. Proc Natl Acad Sci U S A 115:E7814-E7823
Cowell, Annie N; Valdivia, Hugo O; Bishop, Danett K et al. (2018) Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing. Genome Med 10:52
Horton, Lucy E; Haste, Nina M; Taplitz, Randy A (2018) Rethinking Antimicrobial Prophylaxis in the Transplant Patient in the World of Emerging Resistant Organisms-Where Are We Today? Curr Hematol Malig Rep 13:59-67
Cowell, Annie N; Loy, Dorothy E; Sundararaman, Sesh A et al. (2017) Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples. MBio 8:
Green, Nella; Hoenigl, Martin; Chaillon, Antoine et al. (2017) Partner services in adults with acute and early HIV infection. AIDS 31:287-293

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