The Division of Allergy and Infectious Diseases at the University of Washington has trained 115 physician-scientists through continuous funding provided by this training grant since its inception in 1976. More than 85% of these trainees remain in research positions. Many have achieved leadership positions such as two that became Deans of Medicine, one that became a Department Chair, 7 that became Division Heads, and 17 others with leadership positions. Trainees that have completed in the past 10 years have had remarkable early success in research careers, including >75% achieving research funding, >50% with K awards, and >90% publishing one or more papers related to their supported research. The continuing objective of the program is to provide post-doctoral training for physician-scientists committed to an academic career in infectious diseases, with particular emphasis on research training. Each trainee selects a mentor for detailed research training in one of six research tracks. All trainees complete a core curriculum consisting of required didactic, research and clinical activities. Many trainees elect to take course work at the University of Washington and an average of two a year seek a MPH or MSc award. The program generally requires three years of training, two of which are supported by this training grant.

Public Health Relevance

Infectious diseases continue to extract a considerable social and financial toll even in developed countries due to factors such as emerging pathogens, AIDS or other immuno-compromising conditions and antimicrobial resistance;in fact, they represent the leading cause of morbidity and mortality worldwide. The training of new scientists-physicians who can elucidate the basic mechanisms of host defense is critical for the formulation of new and improved strategies to diagnose, treat and prevent infectious diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007044-39
Application #
8667975
Study Section
Transplantation Biology &Immunology-2 (AITC)
Program Officer
Robbins, Christiane M
Project Start
1976-07-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
39
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Seattle
State
WA
Country
United States
Zip Code
98195
Simmons, Jason D; Stein, Catherine M; Seshadri, Chetan et al. (2018) Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection. Nat Rev Immunol 18:575-589
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Hahn, William O; Butler, Noah S; Lindner, Scott E et al. (2018) cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses. JCI Insight 3:
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Tenforde, Mark W; Scriven, James E; Harrison, Thomas S et al. (2017) Immune correlates of HIV-associated cryptococcal meningitis. PLoS Pathog 13:e1006207
Heumann, Christine L; Quilter, Laura A S; Eastment, McKenna C et al. (2017) Adverse Birth Outcomes and Maternal Neisseria gonorrhoeae Infection: A Population-Based Cohort Study in Washington State. Sex Transm Dis 44:266-271
Tenforde, Mark W; Mokomane, Margaret; Leeme, Tshepo et al. (2017) Advanced Human Immunodeficiency Virus Disease in Botswana Following Successful Antiretroviral Therapy Rollout: Incidence of and Temporal Trends in Cryptococcal Meningitis. Clin Infect Dis 65:779-786

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