Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007273-07
Application #
3531077
Study Section
Allergy & Clinical Immunology-1 (AITC)
Project Start
1984-07-01
Project End
1994-06-30
Budget Start
1990-07-01
Budget End
1991-06-30
Support Year
7
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Monteith, Andrew J; Vincent, Heather A; Kang, SunAh et al. (2018) mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a. J Immunol 201:371-382
Kroger, Charles J; Clark, Matthew; Ke, Qi et al. (2018) Therapies to Suppress ? Cell Autoimmunity in Type 1 Diabetes. Front Immunol 9:1891
Cheng, Ning; Watkins-Schulz, Rebekah; Junkins, Robert D et al. (2018) A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer. JCI Insight 3:
Allard, Denise E; Wang, Yan; Li, Jian Joel et al. (2018) Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment. J Clin Invest 128:4727-4741
Junkins, Robert D; Gallovic, Matthew D; Johnson, Brandon M et al. (2018) A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. J Control Release 270:1-13
Hagar, Jon A; Edin, Matthew L; Lih, Fred B et al. (2017) Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock. J Immunol 199:3634-3643
Swanson, Karen V; Junkins, Robert D; Kurkjian, Cathryn J et al. (2017) A noncanonical function of cGAMP in inflammasome priming and activation. J Exp Med 214:3611-3626
Taylor, Nicholas A; Vick, Sarah C; Iglesia, Michael D et al. (2017) Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer. J Clin Invest 127:3472-3483
Manzoor, Fatima; Johnson, Mark C; Li, Chengwen et al. (2017) ?-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice. Eur J Immunol 47:144-154
Clark, Matthew; Kroger, Charles J; Tisch, Roland M (2017) Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response. Front Immunol 8:1898

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