Parasitic diseases caused by protozoans and helminths, as well as arthropod-vectored viral diseases, continue to plague much of the developing world. Even in industrialized nations, poorer communities are deeply affected by parasitology and arboviral diseases, especially in the southern Gulf coast region of the United States. The United States has also seen the emergence of new human pathogens (e.g., Cyclospora, Chikungunya and Zika Viruses), as well as the re-emergence of well-known pathogens such as West Nile or Dengue Viruses. What is needed to combat these devastating infections is a new generation of researchers focused on parasitology and arboviral diseases; however, there are only a few NIH T32s focused on parasitology and vector-borne infectious diseases. One of these T32s is the Parasitology and Vector Biology (PVB) Training Program at the University of Wisconsin-Madison. The goal of the PVB training program is to attract and train the next generation of parasitology/arboviral/vector biology investigators by providing opportunities to study significant, cutting-edge research problems associated with the most important neglected tropical diseases. This goal will be accomplished by trainees acquiring a solid foundation of basic to advanced knowledge through formal coursework, small focus groups and seminars, and combining this knowledge with the latest technologies to address challenging questions posed by a variety of host-pathogen systems available in the laboratories of our 14 faculty trainers. Funding for this renewal is requested for 5 years to support 4 predoctoral trainees per year. After matriculating into one of three main graduate degree programs, new-entry or post-dissertator PVB trainees will be appointed for 2 years. In addition to meeting their degree program requirements, trainees also are required to complete a research ethics course, complete an individual development plan and update it yearly, and present their research annually in the PVB seminar series. In an effort to increase the diversity of graduate students seeking advanced degrees in parasitology and tropical medicine, plans are described to identify and recruit under-represented minority (URM) students. The plan enacted during the last cycle was highly effective as half of our PVB trainees are URMs. Providing cutting edge and well-rounded training in molecular parasitology and arboviral biology for predoctoral trainees has been and will continue to be our mission. Given the worldwide need to combat these infections, we must train the next generation to think broadly about parasite and arthropod-vectored diseases so that novel solutions to the devastation they cause can be found.

Public Health Relevance

Diseases caused by protozoan and helminth parasites and arthropod-vectored viruses continue to affect millions of people in resource-poor developing countries, despite a vast accumulation of basic and clinical knowledge about these infectious agents. The goal of the current training program in Parasitology and Vector Biology is to recruit and train the next generation of investigators whose focus is on understanding the basic mechanisms regulating host-pathogen interactions and human transmission, thereby contributing to global efforts to control these devastating diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
2T32AI007414-26A1
Application #
9793284
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Coomes, Stephanie
Project Start
1992-07-01
Project End
2024-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
26
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
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