The purpose of the program is to provide opportunity for research training related to dermatology. The need for qualified persons for dermatology research and teaching in academic centers has been well documented. All trainees will be at the post-doctoral level. Primary emphasis will be on research training and, while supported by this training grant, the trainees will be expected to devote essentially their full time to developing their research and scholarly skills. Use will be made in the training program of research expertise both within the Department of Dermatology and from the University at large. Within the Department, Dr. Briggaman's research involves the study of epidermal-dermal interactions and the epidermal-dermal junction and is supported by a NIH research grant. Dr. O'Keefe's research activities concern the biochemistry and cell biology of epidermal cell adhesion and is supported by a grant from the NIH. Dr. McCauliffe's investigation involves the pathomechanism of lupus erythematosus focusing on Ro/SSA autoantigen and is supported by a grant from NIH. Dr. Fine's investigation involves the composition of the skin basement membrane as well as clinical investigation of epidermolysis bullosa. These studies are supported by NIH funding.
| Culton, Donna A; Diaz, Luis A (2012) Treatment of subepidermal immunobullous diseases. Clin Dermatol 30:95-102 |
| Flores, Gustavo; Culton, Donna A; Prisayanh, Phillip et al. (2012) IgG autoantibody response against keratinocyte cadherins in endemic pemphigus foliaceus (fogo selvagem). J Invest Dermatol 132:2573-80 |
| Qian, Ye; Prisayanh, Phillip; Andraca, Eugenio et al. (2011) IgE, IgM, and IgG4 anti-desmoglein 1 autoantibody profile in endemic pemphigus foliaceus (fogo selvagem). J Invest Dermatol 131:985-7 |
| Aoki, Valeria; Sousa Jr, Joaquim Xavier; Diaz, Luis A et al. (2011) Pathogenesis of endemic pemphigus foliaceus. Dermatol Clin 29:413-8, viii |
| Culton, Donna A; Rubenstein, David S; Diaz, Luis A (2010) The resident retreat for future academicians. J Invest Dermatol 130:1775-7 |
| Qian, Ye; Clarke, Stephen H; Aoki, Valeria et al. (2009) Antigen selection of anti-DSG1 autoantibodies during and before the onset of endemic pemphigus foliaceus. J Invest Dermatol 129:2823-34 |
| Heimbach, L; Li, N; Diaz, A et al. (2009) Experimental animal models of bullous pemphigoid. G Ital Dermatol Venereol 144:423-31 |
| Qaqish, Bahjat F; Prisayanh, Phillip; Qian, Ye et al. (2009) Development of an IgG4-based predictor of endemic pemphigus foliaceus (fogo selvagem). J Invest Dermatol 129:110-8 |
| Culton, Donna A; Qian, Ye; Li, Ning et al. (2008) Advances in pemphigus and its endemic pemphigus foliaceus (Fogo Selvagem) phenotype: a paradigm of human autoimmunity. J Autoimmun 31:311-24 |
| Evangelista, Flor; Dasher, David A; Diaz, Luis A et al. (2008) E-cadherin is an additional immunological target for pemphigus autoantibodies. J Invest Dermatol 128:1710-8 |
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