The proposed training program in dermatology will provide fundamental training at the pre and post-doctoral level in basic and clinical research as it relates to the skin. This program will fulfill a unique niche in dermatology because the training grant faculty have expertise in bioengineering as well as biology and health services research. The expertise in biological problems relating to skin resides primarily within the department of dermatology, including keratinocyte function, melanocyte function, and immunology. These studies require diverse laboratory approaches involving enzymology, recombinant DNA technology, lipid biochemistry and gene regulation enabling a trainee to gain broad laboratory expertise. Trainees interested in Health Services research can train in collaboration with the Department of Community Medicine under the direction of Dr. Thomas Pearson. Finally, pre-doctoral and/or post-doctoral candidates interested in the interface between technology and medicine will have the opportunity to train under the auspices of the Bioengineering, Science and Technology Systems Center, where their research can focus on interdisciplinary applications for skin disease in collaboration with the faculty of the Departments of Engineering and Computer Sciences. The post-doctoral program is preferable of three years duration and is aimed at training promising physicians and Ph.D.'s for academic careers. The post-doctoral program is preferably of three years duration and is aimed at training promising physicians and Ph.D.'s for academic careers. The availability of excellent research facilities in our department, the Medical School and in the Bioengineering, Science and Technology Systems Center permits sufficient flexibility in our program to suit the special interest of each trainee. Support is requested for three postdoctoral trainees who have received the degree of either M.D. or Ph.D. An additional slot is requested for a pre- doctoral trainee, to be increased to two in th third year of the grant. Highly qualified candidates are selected from our clinical training program and/or from outside applicants applying directly to our research program, or through the Computer Sciences/Bioengineering Pre-doctoral program. This program is intended to train individuals whose future activities will be based on a research academic career in Dermatology and the applicants must have a firm commitment to pursue a full-time academic career.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR007472-14
Application #
6511771
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Moshell, Alan N
Project Start
1987-07-01
Project End
2004-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
14
Fiscal Year
2002
Total Cost
$134,511
Indirect Cost
Name
University of Rochester
Department
Dermatology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Baker, James E; Sriram, Rashmi; Miller, Benjamin L (2017) Recognition-mediated particle detection under microfluidic flow with waveguide-coupled 2D photonic crystals: towards integrated photonic virus detectors. Lab Chip 17:1570-1577
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Baker, James E; Sriram, Rashmi; Miller, Benjamin L (2015) Two-dimensional photonic crystals for sensitive microscale chemical and biochemical sensing. Lab Chip 15:971-990
Baker, James E; Miller, Benjamin L (2015) Discrimination of ""specific"" and ""nonspecific"" binding in two-dimensional photonic crystals. Opt Express 23:7101-10
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Kuo, I-Hsin; Carpenter-Mendini, Amanda; Yoshida, Takeshi et al. (2013) Activation of epidermal toll-like receptor 2 enhances tight junction function: implications for atopic dermatitis and skin barrier repair. J Invest Dermatol 133:988-98
Soong, Joanne; Scott, Glynis (2013) Plexin B1 inhibits MET through direct association and regulates Shp2 expression in melanocytes. J Cell Sci 126:688-95
Pentland, Alice (2013) Building social and scientific networks to grow our global skin biology community. J Invest Dermatol 133:2497-2499
De Benedetto, Anna; Kubo, Akiharu; Beck, Lisa A (2012) Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol 132:949-63
Myakishev-Rempel, Max; Stadler, Istvan; Brondon, Philip et al. (2012) A preliminary study of the safety of red light phototherapy of tissues harboring cancer. Photomed Laser Surg 30:551-8

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