Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009030-10
Application #
3532283
Study Section
Cancer Institutional Fellowship Review Committee (CT)
Project Start
1975-06-30
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1987-06-30
Support Year
10
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Barbosa, M S; Vass, W C; Lowy, D R et al. (1991) In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential. J Virol 65:292-8
Barbosa, M S; Edmonds, C; Fisher, C et al. (1990) The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation. EMBO J 9:153-60
Lampe, M A; Kammerer, R C (1990) Species differences in the metabolism and macromolecular binding of methapyrilene: a comparison of rat, mouse and hamster. Xenobiotica 20:1269-80
Barbosa, M S; Schlegel, R (1989) The E6 and E7 genes of HPV-18 are sufficient for inducing two-stage in vitro transformation of human keratinocytes. Oncogene 4:1529-32
Barbosa, M S; Lowy, D R; Schiller, J T (1989) Papillomavirus polypeptides E6 and E7 are zinc-binding proteins. J Virol 63:1404-7
Kammerer, R C; Schmitz, D A; Lampe, M A et al. (1988) The in vivo metabolism of methapyrilene, a hepatocarcinogen, in the rat. Xenobiotica 18:869-81
Lampe, M A; Kammerer, R C (1987) Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro. Carcinogenesis 8:1525-9
Kammerer, R C; Lampe, M A (1987) In vitro metabolism of chlorpheniramine in the rabbit. Biochem Pharmacol 36:3445-52
Kammerer, R C; Kloc, K; Lampe, M A et al. (1987) Oxidation of the pyridine ring: a major pathway of metabolism for the rat hepatocarcinogen, methapyrilene. Proc West Pharmacol Soc 30:79-83
Lampe, M A; Kammerer, R C (1987) The effect of chronic methapyrilene treatment on methapyrilene metabolism in vitro. Carcinogenesis 8:221-6

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