Abstract

Program Characteristics: This predoctoral program in the Department of Oncology of the McArdle Laboratory for Cancer Research at the University of Wisconsin is now in its twentieth year. Dr. Bill Sugden has been the director since 1987; Dr. Henry Pitot was the previous director. Seventeen faculty, with both basic and clinical science credentials, direct a total of 38 students. Trainees have an established curriculum of coursework, examinations, seminars, and research. There is a decided cancer focus in the required curriculum. The average length of time for completion of the requirements for the Ph.D. degree is 5.5 years. Trainees are supervised by individual mentors and through a committee structure. Approximately two-thirds of eligible predoctoral students are supported for at least part of their period in graduate school.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009135-25
Application #
2894346
Study Section
Cancer Institutional Fellowship Review Committee (CT)
Program Officer
Gorelic, Lester S
Project Start
1975-07-01
Project End
2000-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
25
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Shea, Michael P; O'Leary, Kathleen A; Fakhraldeen, Saja A et al. (2018) Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ER?+ Mammary Carcinomas. Cancer Res 78:1672-1684
Helzer, Kyle T; Ozers, Mary Szatkowski; Meyer, Mark B et al. (2018) The Phosphorylated Estrogen Receptor Cistrome Identifies a Subset of Active Enhancers Enriched for Direct ER-DNA Binding and the Transcription Factor GRHL2. Mol Cell Biol :
Jallow, Fatou; Brockman, Jennifer L; Helzer, Kyle T et al. (2018) 17?-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes. J Endocr Soc 2:293-309
Evans 3rd, Edward L; Becker, Jordan T; Fricke, Stephanie L et al. (2018) HIV-1 Vif's Capacity To Manipulate the Cell Cycle Is Species Specific. J Virol 92:
Bristol, Jillian A; Djavadian, Reza; Albright, Emily R et al. (2018) A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection. PLoS Pathog 14:e1007179
Romero-Masters, James C; Ohashi, Makoto; Djavadian, Reza et al. (2018) An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model. PLoS Pathog 14:e1007221
Huynh, Mailee; Pak, Chorom; Markovina, Stephanie et al. (2018) Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-?B activity and increases drug resistance in multiple myeloma. J Biol Chem 293:2452-2465
Guo, Feng; Wlodarchak, Nathan; Menden, Patrick et al. (2018) Purification of Target Proteins from Native Tissues: CCT Complex from Bovine Testes and PP2Ac from Porcine Brains. Methods Mol Biol 1788:73-88
Barault, Ludovic; Amatu, Alessio; Siravegna, Giulia et al. (2018) Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. Gut 67:1995-2005
Damodaran, Shivashankar; Damaschke, Nathan; Gawdzik, Joseph et al. (2017) Dysregulation of Sirtuin 2 (SIRT2) and histone H3K18 acetylation pathways associates with adverse prostate cancer outcomes. BMC Cancer 17:874

Showing the most recent 10 out of 333 publications