The goal of this program is to train MD postdoctoral fellows in biomedical research as it applies to Oncology. We offer a multi- disciplinary program that consists of didactic instruction, seminars, and supervised research. Important elements of the curriculum are supervision by faculty advisors, formal course work, interactions between the trainee and the entire faculty, and interactions between the trainee and his/her peers. Dr. Theodore G. Krontiris is the Program Director. Faculty of the training program include many members of the Hematology-Oncology Division of New England Medical Center and Tufts University School of Medicine supplemented by additional basic science faculty at Tufts University School of Medicine that offer research opportunities within the context of the research theme, """"""""Molecular Aspects of Neoplasia."""""""" The program is designed to develop medical scientists who understand the basic principles of biological research, and who will be able to apply these principles independently to investigations relevant to the field of Oncology. MD trainees are selected from about 100 applicants each year. Only those applicants with an explicit commitment to a career in academic medicine and basic research are selected. The training plan is an integral part of the Division's training program in Hematology-Oncology for physicians planning careers in academic medicine. It consists of a minimum of two years of supervised bench research and didactic instruction after completion of the major part of clinical subspecialty training (funded by New England Medical Center). We also receive applications from physicians applying solely for research training. The design of the program has been revised to take into account several factors that have become particularly evident in the past five years: (a) The need for physicians beginning research work after a long period of medical training to acquire knowledge of advances in genetics, molecular biology, protein biochemistry, and cell biology; (b) the need for an extended training experience to allow fellows to develop sophistication in modem, complex biomedical research; (c) the almost universal requirement for physicians embarked on academic careers in teaching hospitals to attain certification by the American Board of Oncology and, usually, the American Board of Hematology; (d) severe economic pressures; and (e) increasingly severe competition for NIH funds. This training program, now in its 15th year, has provided a comprehensive and nurturing environment to support the successful scientific training of medical scientists entering this increasingly demanding academic world.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009429-19
Application #
2894386
Study Section
Cancer Research Manpower and Education Review Committee (CRME)
Program Officer
Damico, Mark W
Project Start
1981-09-01
Project End
2001-08-31
Budget Start
1999-09-09
Budget End
2000-08-31
Support Year
19
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Shah, Gunjan L; Winn, Aaron; Lin, Pei-Jung et al. (2016) Cost Implications of Comorbidity for Autologous Stem Cell Transplantation in Elderly Patients with Multiple Myeloma Using SEER-Medicare. Bone Marrow Res 2016:3645623
Buchsbaum, Rachel J; Oh, Sun Young (2016) Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go. Cancers (Basel) 8:
Xu, Kun; Tian, Xuejun; Oh, Sun Y et al. (2016) The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis. Breast Cancer Res 18:14
Winn, Aaron N; Shah, Gunjan L; Cohen, Joshua T et al. (2015) The real world effectiveness of hematopoietic transplant among elderly individuals with multiple myeloma. J Natl Cancer Inst 107:
Saret, Cayla J; Winn, Aaron N; Shah, Gunjan et al. (2015) Value of innovation in hematologic malignancies: a systematic review of published cost-effectiveness analyses. Blood 125:1866-9
Shah, Gunjan L; Winn, Aaron N; Lin, Pei-Jung et al. (2015) Cost-Effectiveness of Autologous Hematopoietic Stem Cell Transplantation for Elderly Patients with Multiple Myeloma using the Surveillance, Epidemiology, and End Results-Medicare Database. Biol Blood Marrow Transplant 21:1823-9
Shah, Gunjan L; Rosenberg, Aaron S; Jarboe, Jamie et al. (2014) Incidence and evaluation of incidental abnormal bone marrow signal on magnetic resonance imaging. ScientificWorldJournal 2014:380814
Ahmed, Wesam; Van Etten, Richard A (2013) Signal transduction in the chronic leukemias: implications for targeted therapies. Curr Hematol Malig Rep 8:71-80
Ahmed, Wesam; Van Etten, Richard A (2013) Alternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond. Hematology Am Soc Hematol Educ Program 2013:189-200
Shah, Gunjan; Yamin, Hanah; Smith, Hedy (2013) Mitomycin-C-Induced TTP/HUS Treated Successfully with Rituximab: Case Report and Review of the Literature. Case Rep Hematol 2013:130978

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