This application is submitted by Brigham and Women's Hospital (BWH), a Harvard- affiliated teaching hospital located in Boston, and requests funding to continue a training program for cancer surgeons, the Advanced Training in Surgical Oncology (ATSO) program. ATSO supports laboratory-based cancer research for surgical residents who wish to pursue a career in general surgical or thoracic oncology. The program is primarily directed toward residents from BWH, but also includes other Harvard-affiliated residencies and postgraduate programs throughout the United States. ATSO leaders also make a deliberate attempt to recruit applicants from underrepresented minorities. The overall goal of ATSO is to dramatically improve care of cancer patients by training surgeon-scientists who will devote their careers to studying and implementing biologically-based cancer treatment. This goal is particularly important now, as surgeons are at the forefront of the revolution in personalized medicine. The ATSO program achieves this aim by exposing surgical residents to the best discovery and translational research available in the Harvard system, placing them in laboratories led by mentors who are accomplished scientists and educators. ATSO includes formal didactic sessions to familiarize trainees with the fundamentals of basic, translational and clinical research, including programs in research ethics. Through the work of its Governance Board, ATSO provides frequent career development and progress review interactions with trainees and the ATSO itself is continually enriched through formal evaluations by its Advisory Board and the trainees themselves. Our well-established program has a solid record of success, with 91% of post-ATSO trainees from the last 10 years successfully pursuing a career in academic medicine. We look forward to improving this record even further by meeting the challenges of an ever-increasing societal need for talented, well-trained and well-supported surgeon-scientists.

Public Health Relevance

Modern cancer care is multidisciplinary, biologically-based and usually starts in the surgeon's office. Cancer care will improve if surgeons wishing to pursue an academic career receive education in gene discovery, target and biomarker validation, cancer biology and the development of targeted therapies. If surgeons participate in research, the pace of discovery and improvement in cancer care will accelerate.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
2T32CA009535-24A2
Application #
8151720
Study Section
Subcommittee G - Education (NCI)
Program Officer
Damico, Mark W
Project Start
1985-03-01
Project End
2016-06-30
Budget Start
2011-07-14
Budget End
2012-06-30
Support Year
24
Fiscal Year
2011
Total Cost
$319,809
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Servais, Andrew B; Kienzle, Arne; Ysasi, Alexandra B et al. (2018) Structural heteropolysaccharides as air-tight sealants of the human pleura. J Biomed Mater Res B Appl Biomater :
Kienzle, Arne; Servais, Andrew B; Ysasi, Alexandra B et al. (2018) Free-Floating Mesothelial Cells in Pleural Fluid After Lung Surgery. Front Med (Lausanne) 5:89
Sharma, Gaurav; Kuppler, Christopher; He, Yong et al. (2018) Local Adipose-Associated Mediators and Adaptations Following Arteriovenous Fistula Creation. Kidney Int Rep 3:970-978
Digesu, Christopher S; Hachey, Krista J; Gilmore, Denis M et al. (2018) Long-term outcomes after near-infrared sentinel lymph node mapping in non-small cell lung cancer. J Thorac Cardiovasc Surg 155:1280-1291
Digesu, Christopher S; Weiss, Kathleen D; Colson, Yolonda L (2018) Near-Infrared Sentinel Lymph Node Identification in Non-Small Cell Lung Cancer. JAMA Surg 153:487-488
Dodgion, Christopher M; Lipsitz, Stuart R; Decker, Marquita R et al. (2017) Institutional variation in surgical care for early-stage breast cancer at community hospitals. J Surg Res 211:196-205
Ohman, Kerri A; Liu, Jingxia; Linehan, David C et al. (2017) Interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: long-term follow-up. HPB (Oxford) 19:449-457
Aycart, Mario A; Alhefzi, Muayyad; Sharma, Gaurav et al. (2017) Outcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements: A Nationwide Analysis. Transplantation 101:1381-1386
Bennett, Robert D; Ysasi, Alexandra B; Wagner, Willi L et al. (2017) Deformation-induced transitional myofibroblasts contribute to compensatory lung growth. Am J Physiol Lung Cell Mol Physiol 312:L79-L88
Cusworth, Brian M; Krasnick, Bradley A; Nywening, Timothy M et al. (2017) Whipple-specific complications result in prolonged length of stay not accounted for in ACS-NSQIP Surgical Risk Calculator. HPB (Oxford) 19:147-153

Showing the most recent 10 out of 92 publications