The Department of Surgery at the Washington School of Medicine (WUSM) requests continued funding to support a training grant in surgical oncology for surgical house officers who are planning careers in the specialties of general surgery, pediatric surgery, plastic surgery, and thoracic surgery. The grant will support an educational program in laboratory research in one of four basic science fields related to oncology: cell and integrative biology, immunobiology, molecular biology and molecular genetics. From three to five house officers, are selected annually for this research training program through a rigorous and highly competitive process. The majority of surgical oncology trainees will be from the Washington University School of Medicine, although on occasion, surgical residents from other clinical programs will be accepted. Thus far approximately seventy percent of participating resident surgeons, through intensive educational programs and monitored experiences in laboratory research, to become independent scientific investigators. Upon completing the research training program and the residency in clinical surgery the graduates are positioned to acquire faculty positions in academic departments of surgery to become leading clinical scientists. The success of this program to date is attested to by the fact that eleven house officers who have completed this research training program, and have subsequently completed their clinical residency, ten(90 percent) now hold full-time positions in academic departments of surgery in the United States. The Department of Surgery at the WUSM has 58,000 net square feet of laboratory research space including 45,000 net square feet in the Clinical Sciences Research Building (CSRB). In addition the basic science faculty members who will serve as preceptors occupy laboratory space totalling 21,000 net square feet. The relevant research laboratories are located in the CSRB, the McDonnel Sciences Building, the Cancer Research Building, and the Howard Hughes Medical Institute. The participating clinical science and basic science faculties have grant support in excess of $10,000,000. The clinical training of the residents will be in the clinical facilities of the Barnes-Jewish Health Care System. In 1997 there were 4,232 newly diagnosed cases of malignancy admitted to the hospital.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
2T32CA009621-11
Application #
2720135
Study Section
Subcommittee G - Education (NCI)
Program Officer
Eckstein, David J
Project Start
1988-07-05
Project End
2004-02-29
Budget Start
1999-03-19
Budget End
2000-02-29
Support Year
11
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Washington University
Department
Surgery
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Rosen, David R; Wolfe, Rachel C; Damle, Aneel et al. (2018) Thoracic Epidural Analgesia: Does It Enhance Recovery? Dis Colon Rectum 61:1403-1409
Durai, Vivek; Bagadia, Prachi; Briseño, Carlos G et al. (2018) Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice. J Exp Med 215:1417-1435
Semenkovich, Tara R; Panni, Roheena Z; Hudson, Jessica L et al. (2018) Comparative effectiveness of upfront esophagectomy versus induction chemoradiation in clinical stage T2N0 esophageal cancer: A decision analysis. J Thorac Cardiovasc Surg 155:2221-2230.e1
Schimizzi, Gregory V; Jin, Linda X; Davidson 4th, Jesse T et al. (2018) Outcomes after vascular resection during curative-intent resection for hilar cholangiocarcinoma: a multi-institution study from the US extrahepatic biliary malignancy consortium. HPB (Oxford) 20:332-339
Merath, Katiuscha; Bagante, Fabio; Beal, Eliza W et al. (2018) Nomogram predicting the risk of recurrence after curative-intent resection of primary non-metastatic gastrointestinal neuroendocrine tumors: An analysis of the U.S. Neuroendocrine Tumor Study Group. J Surg Oncol 117:868-878
Theisen, Derek J; Davidson 4th, Jesse T; Briseño, Carlos G et al. (2018) WDFY4 is required for cross-presentation in response to viral and tumor antigens. Science 362:694-699
Panni, Roheena Z; Strasberg, Steven M (2018) Preoperative predictors of conversion as indicators of local inflammation in acute cholecystitis: strategies for future studies to develop quantitative predictors. J Hepatobiliary Pancreat Sci 25:101-108
Briseño, Carlos G; Satpathy, Ansuman T; Davidson 4th, Jesse T et al. (2018) Notch2-dependent DC2s mediate splenic germinal center responses. Proc Natl Acad Sci U S A 115:10726-10731
Nandy, S; Chapman Jr, W; Rais, R et al. (2018) Label-free quantitative optical assessment of human colon tissue using spatial frequency domain imaging. Tech Coloproctol 22:617-621
Brauer, David G; Ohman, Kerri A; Jaques, David P et al. (2018) Surgeon Variation in Intraoperative Supply Cost for Pancreaticoduodenectomy: Is Intraoperative Supply Cost Associated with Outcomes? J Am Coll Surg 226:37-45.e1

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